Volume 45, Issue 6 pp. 1034-1037

Physiological response to a speech stressor presented in a virtual reality environment

Michael Kotlyar

Michael Kotlyar

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

Department of Psychiatry, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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Christopher Donahue

Christopher Donahue

Department of Psychiatry, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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Paul Thuras

Paul Thuras

Department of Psychiatry, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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Matt G. Kushner

Matt G. Kushner

Department of Psychiatry, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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Natalie O'Gorman

Natalie O'Gorman

College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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Erin A Smith

Erin A Smith

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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David E. Adson

David E. Adson

Department of Psychiatry, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA

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First published: 15 October 2008
Citations: 46
Address reprint requests to: Michael Kotlyar, PharmD, University of Minnesota College of Pharmacy, Department of Experimental and Clinical Pharmacology, 7-170 Weaver-Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455. E-mail: [email protected]

This research was supported in part by Grant K23DA017307 to the first author from the National Institute on Drug Abuse and Grant M01-RR00400 from the General Clinical Research Centers program of the National Center for Research Resources.

Abstract

The feasibility of using virtual reality (VR) technology to induce a physiological response to stress was assessed in 12 volunteers during a laboratory session in which each participant completed a speech task within a VR environment and a math task outside the VR environment. Both tasks were effective in eliciting a physiological response with significant increases observed in response to each stress task in systolic and diastolic blood pressure and heart rate. Increases in plasma epinephrine and norepinephrine concentrations were observed during the speech task and in plasma epinephrine concentrations during the math task although these differences did not reach statistical significance. The use of VR technology may be a viable alternative to methods currently employed in presenting stressful tasks with the potential advantage of decreased variability in the audience response to the participants' performance.

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