Sumatriptan causes parallel decrease in plasma CGRP concentration and migraine headache during nitroglycerin-induced migraine attack
F Vanmolkot
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this authorB Van der Schueren
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this authorJ De Hoon
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this authorF Vanmolkot
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this authorB Van der Schueren
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this authorJ De Hoon
Centre for Clinical Pharmacology, University Hospital Gasthuisberg (K.U.Leuven), Leuven, Belgium. E-mail [email protected]
Search for more papers by this author
References
- 1 Arulmani U, Maassenvandenbrink A, Villalon CM, Saxena PR. Calcitonin gene-related peptide and its role in migraine pathophysiology. Eur J Pharmacol 2004; 500: 315–30.
- 2 Goadsby PJ, Edvinsson L, Ekman R. Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann Neurol 1990; 28: 183–7.
- 3 Gallai V, Sarchielli P, Floridi A, Franceschini M, Codini M, Glioti G et al. Vasoactive peptide levels in the plasma of young migraine patients with and without aura assessed both interictally and ictally. Cephalalgia 1995; 15: 384–90.
- 4 Sarchielli P, Alberti A, Codini M, Floridi A, Gallai V. Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacks. Cephalalgia 2000; 20: 907–18.
- 5 Sarchielli P, Alberti A, Vaianella L, Pierguidi L, Floridi A, Mazzotta G et al. Chemokine levels in the jugular venous blood of migraine without aura patients during attacks. Headache 2004; 44: 961–8.
- 6 Juhasz G, Zsombok T, Modos EA, Olajos S, Jakab B, Nemeth J et al. NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release. Pain 2003; 106: 461–70.
- 7 Juhasz G, Zsombok T, Jakab B, Nemeth J, Szolcsanyi J, Bagdy G. Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack. Cephalalgia 2005; 25: 179–83.
- 8 Goadsby PJ, Edvinsson L. The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats. Ann Neurol 1993; 33: 48–56.
- 9 Stepien A, Jagustyn P, Trafny EA, Widerkiewicz K. [Suppressing effect of the serotonin 5HT1B/D receptor agonist rizatriptan on calcitonin gene-related peptide (CGRP) concentration in migraine attacks]. Neurol Neurochir Pol 2003; 37: 1013–23.
- 10 Durham PL, Russo AF. Regulation of calcitonin gene-related peptide secretion by a serotonergic antimigraine drug. J Neurosci 1999; 19: 3423–9.
- 11 Arulmani U, Heiligers JP, Garrelds IM, Sanchez-Lopez A, Willems EW, Villalon CM et al. Effects of sumatriptan on capsaicin-induced carotid haemodynamic changes and CGRP release in anaesthetized pigs. Cephalalgia 2004; 24: 717–27.