Volume 47, Issue 7 pp. 288-291

Tinea imbricata: autosomal dominant pattern of susceptibility in a polygamous indigenous family of the Nahuatl zone in Mexico

A. Bonifaz

A. Bonifaz

Departments of Dermatology and Mycology

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J. Araiza

J. Araiza

Departments of Dermatology and Mycology

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Susana Koffman-Alfaro

Susana Koffman-Alfaro

Departments of Dermatology and Mycology

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Vanessa Paredes-Solis

Vanessa Paredes-Solis

Departments of Dermatology and Mycology

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S. Cuevas-Covarrubias

S. Cuevas-Covarrubias

Genetics, Hospital General de México, Mexico City

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M. R. Rivera

M. R. Rivera

Genetics, Hospital General de México, Mexico City

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First published: 12 August 2004
Citations: 18
Dr Alexandro Bonifaz, Zempoala 60-101, Narvarte. México D. F. CP 03020, Mexico City, NM, USA. Tel./Fax: (+55) 5761 3923.
E-mail: [email protected]

Summary

en

We report on 9 confirmed cases of tinea imbricata (Tokelau, infection due to Trichophyton concentricum) out of 16 family members. They had a common mother with three different fathers. The genetic analysis of the family suggests an autosomal dominant pattern of susceptibility. Most cases (8/9) were presented as concentric and lamellar forms. One patient also had onychomycosis due to T. concentricum. Only two out of nine cases had a positive response to trichophytin.

Zusammenfassung

de

Wir berichten über 9 Fälle von Tinea imbricata (Tokelau, Infektion durch Trichophyton concentricum) in drei Familien mit 16 Personen. Diese hatten dieselbe Mutter, aber drei verschiedene Väter. Die genetische Analyse der Familien lässt an ein dominant-autosomales Anfälligkeitsmuster denken. Acht der neun Fälle präsentierten sich als konzentrische, lamellierte Form. Ein Patient hatte auch eine Onychomykose durch T. concentricum. Nur zwei der neun Patienten waren Trichophytin-positiv.

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