Successful liver transplantation for giant cell hepatitis and Coombs-positive hemolytic anemia: A case report
Murat Akyildiz, Zeki Karasu, Cigdem Arikan,
Deniz Nart, Murat Kilic,
Cigdem Arikan
Pediatric Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorMurat Akyildiz, Zeki Karasu, Cigdem Arikan,
Deniz Nart, Murat Kilic,
Cigdem Arikan
Pediatric Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorCigdem Arikan, 250. sok. Mustafa Cukur Sitesi B1 Blk. No. 6 D:1 34020 Bornova, Izmir, Turkey
Tel.: +90-232-3427131
Fax: +90-232-3398838
E-mail: [email protected]
Abstract
Abstract: Giant cell hepatitis (GCH) with autoimmune hemolytic anemia (AHA) is a distinct entity with an aggressive course. Drugs, autoimmunity, and viruses have been implicated in its etiology. Without treatment, liver dysfunction is progressive and fatal. Although succesful immunosuppressive treatment has been reported, a few patients have undergone liver transplantation with recurrence of the primary disease in the allograft. We report, an 18-year-old boy with progressive GCH with AHA without recurrence in the allograft following deceased donor (DD) liver transplantation.
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