Effect of anticoagulants on plasma concentration of macrophage migration inhibitory factor: A pilot study
Corresponding Author
Huiyuan Zhu
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Correspondence
Huiyuan Zhu, Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou 450006, China.
Email: [email protected]
Aiguo Xu, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Email: [email protected]
Search for more papers by this authorShaochun Yan
Department of Cell Biology, School of Basic and Forensic Medicine, Baotou Medical College, Baotou, China
Search for more papers by this authorJingshuo Wu
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Search for more papers by this authorZhong Zhang
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Search for more papers by this authorCorresponding Author
Aiguo Xu
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Correspondence
Huiyuan Zhu, Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou 450006, China.
Email: [email protected]
Aiguo Xu, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Huiyuan Zhu
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Correspondence
Huiyuan Zhu, Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou 450006, China.
Email: [email protected]
Aiguo Xu, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Email: [email protected]
Search for more papers by this authorShaochun Yan
Department of Cell Biology, School of Basic and Forensic Medicine, Baotou Medical College, Baotou, China
Search for more papers by this authorJingshuo Wu
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Search for more papers by this authorZhong Zhang
Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou, China
Search for more papers by this authorCorresponding Author
Aiguo Xu
Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Correspondence
Huiyuan Zhu, Department of Pulmonary and Critical Care Medicine, Zhengzhou Second People's Hospital, Zhengzhou Affiliated Hospital of Jinan University, Zhengzhou 450006, China.
Email: [email protected]
Aiguo Xu, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Email: [email protected]
Search for more papers by this authorHuiyuan Zhu and Shaochun Yan contributed equally to this work.
Funding information: Henan Province Medical Science and Technology Research Project, Grant/Award Number: 2018020737
Open Research
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
REFERENCES
- 1Harris J, VanPatten S, Deen NS, Al-Abed Y, Morand EF. Rediscovering MIF: new tricks for an old cytokine. Trends Immunol. 2019; 40: 447-462.
- 2Zhu H, Yan S, Wu J, et al. Serum macrophage migration inhibitory factor as a potential biomarker to evaluate therapeutic response in patients with allergic asthma: an exploratory study. J Zhejiang Univ Sci B. 2021; 22(6): 512-520.
- 3Patil R, Shukre S, Paranjape R, Thakar M. Heparin and EDTA anticoagulants differentially affect the plasma cytokine levels in humans. Scand J Clin Lab Invest. 2013; 73: 452-455.
- 4Hennø LT, Storjord E, Christiansen D, et al. Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - consequences for defining reference values in healthy humans. Cytokine. 2017; 97: 86-95.
- 5Mizue Y, Nishihira J, Miyazaki T, et al. Quantitation of macrophage migration inhibitory factor (MIF) using the one-step sandwich enzyme immunosorbent assay: elevated serum MIF concentrations in patients with autoimmune diseases and identification of MIF in erythrocytes. Int J Mol Med. 2000; 5(4): 397-403.
- 6Karsten E, Hill CJ, Herbert BR. Red blood cells: the primary reservoir of macrophage migration inhibitory factor in whole blood. Cytokine. 2018; 102: 34-40.
- 7Sarkar M, Barari SK, Mandal DB, et al. The effect of anti-coagulants on the osmotic fragility of erythrocytes in the yak (Poephagus grunniens). Vet J. 1999; 157: 91-93.
- 8Kafka M, Yermiahu T. The effect of EDTA as an anticoagulant on the osmotic fragility of erythrocytes. Clin Lab Haematol. 1998; 20(4): 213-216.
- 9Vincent FB, Nim HT, Lee JPW, Morand EF, Harris J. Effect of storage duration on cytokine stability in human serum and plasma. Cytokine. 2019; 113: 453-457.
- 10Sobierajski J, Hendgen-Cotta UB, Luedike P, et al. Assessment of macrophage migration inhibitory factor in humans: protocol for accurate and reproducible levels. Free Radic Biol Med. 2013; 63: 236-242.
- 11Lin YS, Haynes CL. Impacts of mesoporous silica nanoparticle size, pore ordering, and pore integrity on hemolytic activity. J Am Chem Soc. 2010; 132(13): 4834-4842.
- 12Wiegmann L, de Zélicourt DA, Speer O, et al. Influence of standard laboratory procedures on measures of erythrocyte damage. Front Physiol. 2017; 8: 731.
- 13Urbina A, Godoy-Silva R, Hoyos M, Camacho M. Acute hydrodynamic damage induced by SPLITT fractionation and centrifugation in red blood cells. J Chromatogr B. 2016; 1020: 53-61.
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