Very rare lineage switch from acute myeloid leukemia to mixed phenotype acute leukemia, B/Myeloid, during chemotherapy with no clonal evolution
Laila Nomani
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Search for more papers by this authorJames R. Cook
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Search for more papers by this authorCorresponding Author
Heesun J. Rogers
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Correspondence
Heesun J. Rogers, MD, PhD, Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH.
Email: [email protected]
Search for more papers by this authorLaila Nomani
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Search for more papers by this authorJames R. Cook
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Search for more papers by this authorCorresponding Author
Heesun J. Rogers
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio
Correspondence
Heesun J. Rogers, MD, PhD, Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH.
Email: [email protected]
Search for more papers by this author
REFERENCES
- 1Gagnon GA, Childs CC, LeMaistre A, et al. Molecular heterogeneity in acute leukemia lineage switch. Blood. 1989; 74(6): 2088-2095.
- 2Park M, Koh KN, Kim BE, et al. Lineage switch at relapse of childhood acute leukemia: a report of four cases. J Korean Med Sci. 2011; 26(6): 829-831.
- 3Imataki O, Ohnishi H, Yamaoka G, et al. Lineage switch from precursor B cell acute lymphoblastic leukemia to acute monocytic leukemia at relapse. Int J Clin Oncol. 2010; 15(1): 112-115.
- 4Stass S, Mirro J, Melvin S, et al. Lineage switch in acute leukemia. Blood. 1984; 64(3): 701-706.
- 5Chung HI, Park CJ, Jang SJ, et al. A case of lineage switch from acute lymphoblastic leukemia to acute myeloid leukemia. Korean J Lab Med. 2007; 27(2): 102-105.
- 6Podgornik H, Debeljak M, Žontar D, et al. RUNX1 amplification in lineage conversion of childhood B-cell acute lymphoblastic leukemia to acute myelogenous leukemia. Cancer Genet Cytogenet. 2007; 178(1): 77-81.
- 7Mantadakis E, Danilatou V, Stiakaki E, et al. T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia. Pediatr Blood Cancer. 2007; 48(3): 354-357.
- 8Szczepanski T, Willemse MJ, Kamps W, et al. Molecular discrimination between relapsed and secondary acute lymphoblastic leukemia: proposal for an easy strategy. Med Pediatr Oncol. 2001; 36(3): 352-358.
- 9Dorantes-Acosta E, Pelayo R. Lineage switching in acute leukemias: a consequence of stem cell plasticity? Bone Marrow Res. 2012; 2012: 406796.
- 10Yokoyama A. Molecular mechanisms of MLL-associated leukemia. Int J Hematol. 2015; 101(4): 352-361.
- 11Kawamoto H, Katsura Y. A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid-lymphoid dichotomy. Trends Immunol. 2009; 30(5): 193-200.
- 12Velten L, Haas SF, Raffel S, et al. Human haematopoietic stem cell lineage commitment is a continuous process. Nature Cell Biol. 2017; 19(4): 271-281.
Citing Literature
