Volume 39, Issue 10 pp. 1348-1358
CASE REPORT

Bacterial endocarditis with AACEK (HACEK) organisms

Lindsey R. Kuohn BA

Corresponding Author

Lindsey R. Kuohn BA

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

Correspondence

Lindsey R. Kuohn, BA, Leon H Charney Division of Cardiology, New York University Langone Health, New York, NY, USA.

Email: [email protected]

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Richard Ro MD

Richard Ro MD

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

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Daniel Bamira MD

Daniel Bamira MD

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

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Alan Vainrib MD

Alan Vainrib MD

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

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Robin Freedberg MD

Robin Freedberg MD

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

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Aubrey Galloway MD

Aubrey Galloway MD

Department of Cardiothoracic Surgery, New York University Langone Health, New York, New York, USA

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Mathew R. Williams MD

Mathew R. Williams MD

Department of Cardiothoracic Surgery, New York University Langone Health, New York, New York, USA

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Muhamed Saric MD, PhD

Muhamed Saric MD, PhD

Leon H Charney Division of Cardiology, New York University Langone Health, New York, New York, USA

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First published: 05 October 2022

Abstract

Introduction

Gram-negative organisms of the AACEK group, formerly known as HACEK, rarely cause endocarditis.

Case Series

We present three cases of bacterial endocarditis, involving native and prosthetic valves, caused by AACEK organisms. In two patients, Cardiobacterium hominis was the responsible organism, and in a third, Aggregatibacter aphrophilus was implicated. A dental source of infection was identified in two patients, and in all three patients, the presentation of endocarditis was subacute.

Discussion

This case series highlights the indolent nature of infection with the AACEK organisms. It also demonstrates the crucial role of multimodality imaging, especially transesophageal echocardiography, in the diagnosis of AACEk endocarditis of both native and prosthetic valves, and in delineating the extent of abscess in those with prosthetic valve infection.

CONFLICT OF INTEREST

The authors declare that there is no conflict of interest.

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