Nihal E. Mohamed, Department of Urology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10028, USA.

Email: [email protected]

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Elke Rammant,

Elke Rammant

orcid.org/0000-0001-6130-2502

Department of Human Structure and Repair, Ghent University, Ghent, Belgium

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Tung Ming Leung,

Tung Ming Leung

Department of Urology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA

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John L. Gore,

John L. Gore

Department of Urology, University of Washington, Seattle Cancer Care Alliance, Seattle, WA, USA

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Donna Berry,

Donna Berry

Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, WA, USA

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Barbara Given,

Barbara Given

College of Nursing, Michigan State University, East Lansing, MI, USA

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Cheryl T. Lee,

Cheryl T. Lee

Department of Urology, The Ohio State University, Columbus, OH, USA

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Diane Quale,

Diane Quale

Bladder Cancer Advocacy Network, Bethesda, MD, USA

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Nihal E. Mohamed,

Corresponding Author

Nihal E. Mohamed

[email protected]

Department of Urology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Correspondence

Nihal E. Mohamed, Department of Urology and Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10028, USA.

Email: [email protected]

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First published: 18 March 2022

https://doi.org/10.1111/ecc.13571

Citations: 4

Funding information: National Cancer Institute; American Cancer Society, Grant/Award Numbers: 121193-MRSG-11-103-01-CPPB, 1R03CA165768-01A1

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Abstract

Objectives

Investigating associations between self-efficacy, social support and quality of life (HRQoL) and mediating effects of coping among bladder cancer (BC) patients treated with radical cystectomy (RC).

Methods

A cross-sectional study was conducted from January 2012 to December 2014 with 99 BC patients. An online survey assessed patient characteristics, HRQoL, coping strategies, self-efficacy and social support. A stepwise multiple linear regression model was used.

Results

Self-efficacy and social support were significantly associated with HRQoL. Complete mediation effects of adaptive/maladaptive coping strategies emerged for the associations between self-efficacy and social support with functional well-being (B = 0.247, 95% CI 0.119–0.374, p < 0.001; B = −0.414, 95% CI −0.526 to −0.302, p < 0.001) and total Functional Assessment of Cancer Therapy-Bladder (FACT-BI) (B = 0.779, 95% CI 0.351–1.207, p < 0.001; B = −1.969, 95% CI −2.344 to −1.594, p < 0.001). Maladaptive coping mediated the associations of self-efficacy and social support with physical well-being (B = −0.667, 95% CI −0.752 to −0.516, p < 0.001) and disease-specific symptoms (B = −0.413, 95% CI −0.521 to −0.304, p < 0.001). A partial mediation effect of adaptive coping was found for the association between self-efficacy and social well-being (B = 0.145, 95% CI 0.016–0.273, p < 0.05). Social support was significantly associated with emotional (B = 0.067, 95% CI 0.027–0.108, p < 0.001) and social well-being (B = 0.200, 95% CI 0.146–0.255, p < 0.001).

Conclusion

Interventions should tackle self-efficacy, social support and coping strategies to improve BC patients' HRQoL.

CONFLICT OF INTEREST

None.

Open Research

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

Supporting Information

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ecc13571-sup-0001-Supplementary file. Linear regressions MIBC.docxWord 2007 document , 15.4 KB	File S1 Supporting Information
ecc13571-sup-0002-Supplementary file 2.docxWord 2007 document , 376.4 KB	File S2 Supporting Information

Associations of self-efficacy, social support and coping strategies with health-related quality of life after radical cystectomy for bladder cancer: A cross-sectional study

Abstract

Objectives

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

Supporting Information

REFERENCES

Citing Literature

References

Information

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Associations of self-efficacy, social support and coping strategies with health-related quality of life after radical cystectomy for bladder cancer: A cross-sectional study

Abstract

Objectives

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

Supporting Information

REFERENCES

Citing Literature

References

Related

Information