Clinical study on the correlation between monocyte-related ratios and calcification of the abdominal aorta in peritoneal dialysis patients
Jiani Sun and Yuan Lu contributed equally.
Abstract
Introduction
We aimed to investigate the relationship between monocyte/lymphocyte ratio (MLR) and monocyte/high-density lipoprotein ratio (MHR) with abdominal aortic calcification (AAC) in patients on peritoneal dialysis (PD).
Methods
The time-averaged (TA) of relevant indexes and AAC scores (AACs) of 160 eligible patients were measured.
Results
Patients divided into the new AAC (n = 57) and the other without (n = 82). High TA-MLR (OR = 110.537, p = 0.018) and long duration of dialysis (OR = 1.045, p < 0.001) were independent risk factors of the new AAC. Patients divided into the no AAC (n = 82), the moderate-to-severe AAC (n = 26), and the mild AAC (n = 52). High TA-MLR (OR = 42.649, p = 0.032), high age at starting PD (OR = 1.055, p < 0.001), and long duration of PD (OR = 1.036, p < 0.001) were independent risk factors of AAC severity.
Conclusions
MLR is an independent risk factor for the occurrence and severity of AAC and its value for the assessment of AAC is better than MHR.
CONFLICT OF INTEREST STATEMENT
The authors have no financial conflicts of interest to declare.
