Journal of Pediatric Gastroenterology and Nutrition

Volume 45, Issue 4 pp. 497-499

Short Communications

Ninety Percent of Celiac Disease Is Being Missed

M Ravikumara,

M Ravikumara

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

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VKT Nootigattu,

VKT Nootigattu

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

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BK Sandhu,

Corresponding Author

BK Sandhu

[email protected]

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

Address correspondence and reprint requests to Prof B.K. Sandhu, Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin St, Bristol, BS2 8BJ, UK (e-mail: [email protected]).Search for more papers by this author

M Ravikumara,

M Ravikumara

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

Search for more papers by this author

VKT Nootigattu,

VKT Nootigattu

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

Search for more papers by this author

BK Sandhu,

Corresponding Author

BK Sandhu

[email protected]

Department of Gastroenterology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK

First published: 01 October 2007

https://doi.org/10.1097/MPG.0b013e31812e5710

Citations: 49

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ABSTRACT

Serological screening of 5470 children age 7.5 years from a cohort of 13,971 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) suggested the prevalence of celiac disease (CD) to be at least 1%. ALSPAC is an anonymous study, and hence seropositive children could not be individually identified or undergo biopsy. Inasmuch as all children within ALSPAC suspected of having CD are referred to just 1 center, we aimed to identify children with biopsy-confirmed CD who were likely to be in this cohort and to estimate the magnitude of discrepancy between serology-positive cases and biopsy-confirmed cases. The results suggest that more than 90% of CD in children goes undiagnosed.

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Volume45, Issue4

October 2007

Pages 497-499

Ninety Percent of Celiac Disease Is Being Missed

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Ninety Percent of Celiac Disease Is Being Missed

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