Volume 59, Issue 5 pp. 640-641
Original Articles: Hepatology and Nutrition

Acute Leukemia Presenting as Acute Hepatitis Without Liver Failure

Christine Rivet

Christine Rivet

Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre

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Guy Leverger

Guy Leverger

Hématologie-Immuno-Oncologie Pédiatrique, Hôpital d'Enfants Armand Trousseau, AP-HP, Paris, France

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Emmanuel Jacquemin

Emmanuel Jacquemin

Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre

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Olivier Bernard

Corresponding Author

Olivier Bernard

Hépatologie Pédiatrique and Centre de Référence National de l'Atrésie des Voies Biliaires, Hôpital Bicêtre AP-HP, INSERM U757 Orsay, and Université Paris-Sud 11, Le Kremlin-Bicêtre

Address correspondence and reprint requests to Olivier Bernard, Hépatologie Pédiatrique, Hôpital Bicêtre, Le Kremlin-Bicêtre Cedex 94275, France (e-mail: [email protected]).Search for more papers by this author
First published: 01 November 2014
Citations: 8

The authors report no conflicts of interest.

ABSTRACT

A diagnosis of acute lymphoblastic or myeloblastic leukemia was made in 6 children ages 4 to 14 years who presented with a clinicobiochemical picture of acute hepatitis without liver failure. Standard chemotherapy, including 1 week pretreatment with steroids in children with lymphoblastic leukemia, allowed complete remission of the leukemia and normalization of serum liver tests.

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