Volume 23, Issue 8 pp. 769-773

Blood Flow in a Continuous Flow Ventricular Assist Device

Paul E. Allaire,

Paul E. Allaire

Mechanical, Aerospace and Nuclear Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Houston G. Wood,

Houston G. Wood

Mechanical, Aerospace and Nuclear Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Ramy S. Awad,

Ramy S. Awad

Biomedical Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Don B. Olsen,

Don B. Olsen

Artificial Heart Laboratory, University of Utah, Salt Lake City, Utah, U.S.A.

Search for more papers by this author

Paul E. Allaire,

Paul E. Allaire

Mechanical, Aerospace and Nuclear Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Houston G. Wood,

Houston G. Wood

Mechanical, Aerospace and Nuclear Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Ramy S. Awad,

Ramy S. Awad

Biomedical Engineering Department, University of Virginia, Charlottesville, Virginia,

Search for more papers by this author

Don B. Olsen,

Don B. Olsen

Artificial Heart Laboratory, University of Utah, Salt Lake City, Utah, U.S.A.

Search for more papers by this author

First published: 24 December 2001

https://doi.org/10.1046/j.1525-1594.1999.06420.x

Citations: 31

Dr. Paul E. Allaire University of Virginia, Mechanical Engineering Department, Thornton Hall, Charlottesville, VA 22903, U.S.A.

Presented in part at the 6th Congress of the International Society for Rotary Blood Pumps, July 25–27, 1998, in Park City, Utah, U.S.A.

Share a link

Email
Wechat
Bluesky

Abstract

A numerical analysis was performed to predict the shear stresses, flow rates, and the velocity profiles in a continuous flow ventricular assist device, the CFVAD3. The problem was modeled as a rotating disk over a stationary disk. A variety of clearances was tested for the CFVAD3 coupled with a range of rotational speeds and pressure gradients. Velocity fields were generated using solutions obtained with FLOW3D software (AEA Technology, Pittsburgh, PA, U.S.A.) Analysis of these solutions shows that the pressure differential effect has a stronger influence on the flow than the rotational effect of the impeller Ekman layer. The predicted shear stresses reflect these changes in the volume flow rates and the speeds shown in the velocity profiles. Based on the predictions of the software, the optimum clearance and rotational speed were chosen. The conclusion is that a speed in the range of 2,200–2,400 rpm should be chosen depending on the efficiency of the pump.

References

1 Phillips WM, Brighton JA, Pierce WS. Artificial heart evaluation using flow visualization techniques. Trans Am Soc Artif Intern Organs 1972; 18: 194 201.
10.1097/00002480-197201000-00050
CAS PubMed Web of Science® Google Scholar
2 Miller GE, Madigan M, Fink R. Preliminary flow visualization study in a multiple disk centrifugal artificial ventricle. Artif Organs 1995; 19(7): 680 4.
10.1111/j.1525-1594.1995.tb02402.x
CAS PubMed Web of Science® Google Scholar
3 Meier D, Wernicke JT, Orime Y, Takatani S, Tasai K, Damm G, Naito K, Mizuguchi K, Makinouchi K, Glueck J, Shimono T, Matsuda Y, Ohara Y, Kojima R, Noon GP, DeBakey ME, Nosé Y. Flow pattern analysis of the Baylor total artificial heart. Artif Organs 1994; 18(12): 923 32.
10.1111/j.1525-1594.1994.tb03345.x
CAS PubMed Web of Science® Google Scholar
4 Yeleswarapu KK, Antaki JF, Kamaneva MV, Rajagopal KR. A mathematical model for shear induced hemolysis. Artif Organs 1995; 19(7): 576 82.
10.1111/j.1525-1594.1995.tb02384.x
CAS PubMed Web of Science® Google Scholar
5 Antaki JF, Ghattas O, Burgreen GW, He B. Computational flow optimization of rotary blood pump components. Artif Organs 1995; 19(7): 608 15.
10.1111/j.1525-1594.1995.tb02389.x
CAS PubMed Web of Science® Google Scholar
6 Bludszuweit C. Model for general mechanical blood damage prediction. Artif Organs 1995; 19(7): 583 9.
10.1111/j.1525-1594.1995.tb02385.x
CAS PubMed Web of Science® Google Scholar
7 Sutera SP, Croce PA, Mehrjardi M. Hemolysis and subhemolytic alterations of human RBC induced by turbulent shear flow. Trans Am Soc Artif Intern Organs 1972; 18: 335 41.
10.1097/00002480-197201000-00084
CAS PubMed Web of Science® Google Scholar
8 Schima H, Müller MR, Papantonis D, Schlusche C, Huber L, Schmidt C, Trubel W, Thoma H, Losert U, Wolner E. Minimization of hemolysis in centrifugal blood pumps: Influence of different geometries. Int J Artif Organs 1993; 16(7): 521 9.
10.1177/039139889301600705
CAS PubMed Web of Science® Google Scholar
9 Tamagawa M, Akamatsu T, Saitoh K. Prediction of hemolysis in turbulent shear orifice flow. Artif Organs 1996; 20(6): 553 9.
10.1111/j.1525-1594.1996.tb04479.x
CAS PubMed Web of Science® Google Scholar
10 Sallam AM & Hwang NHC. Human red blood cell hemolysis in a turbulent shear flow: Contribution of Reynolds shear stresses. Biorheology 1984; 21: 783 97.
10.3233/BIR-1984-21605
CAS PubMed Web of Science® Google Scholar
11 Nevaril CG, Lynch EC, Alfrey Jr CP, Hellums D. Erythrocyte damage and destruction induced by shearing stress. J Lab Clin Med 1968; 71(5): 784 90.
CAS PubMed Web of Science® Google Scholar
12 Blackshear PL & Blackshear GL. Mechanical hemolysis. In: Skalak R, Chien S, eds. Handbook of bioengineering. New York: McGraw Hill 1987:501.
Google Scholar
13 Bearnson GB, Olsen DB, Kanwilkar PS, Long JW, Allaire PE, Maslen EH. Pulsatile operation of a centrifugal ventricular assist device with magnetic bearings. ASAIO J 1996; 42(5): M620 4.
10.1097/00002480-199609000-00061
CAS PubMed Web of Science® Google Scholar
14 Kim HC, Bearnson GB, Kanwilkar PS, Olsen DB, Maslen EH, Allaire PE. In vitro characterization of a magnetically suspended continuous flow ventricular assist device. ASAIO J 1995; 41(3): M359 64.
10.1097/00002480-199507000-00031
CAS PubMed Web of Science® Google Scholar
15 Bearnson GB, Maslen EH, Olsen DB, Allaire PE, Kanwilkar PS, Long JW, Kim HC. Development of a prototype magnetically suspended rotor ventricular assist device. ASAIO J 1996; 42(4): 275 81.
10.1097/00002480-199642040-00009
CAS PubMed Web of Science® Google Scholar
16 Allaire PE, Kim HC, Maslen EH, Olsen DB, Bearnson GB. Prototype continuous flow ventricular assist device supported on magnetic bearings. Artif Organs 1996; 20(6): 582 90.
10.1111/j.1525-1594.1996.tb04486.x
PubMed Web of Science® Google Scholar
17 Kanwilkar PS, Olsen DB, Bearnson GB, Allaire PE, Maslen EH, Flack RD, Long JW. Using hybrid magnetic bearings to completely suspend the impeller of a ventricular assist device. Artif Organs. 1996; 20(6): 597 604.
10.1111/j.1525-1594.1996.tb04488.x
PubMed Web of Science® Google Scholar
18 Cooney DO. The rheologic properties of blood. In: Biomedical engineering principles. New York: Marcel Dekkar, 1976:51.
Google Scholar
19 Fung YC. Blood rheology. In: Biomechanics. New York: Springer-Verlag, 1984:64.
Google Scholar
20 Blackshear Jr PL, Dorman FD, Steinbach JH, Mayback EJ, Singh A, Collingham RE. Shear, wall interaction and hemolysis. Trans Am Soc Artif Intern Organs 1966; 12: 113 20.
CAS PubMed Web of Science® Google Scholar
21 Wakisaka Y, Taenaka Y, Nakatani T, Anai H, Araki K, Nishimura T, Tatsumi E, Masuzawa T, Baba Y, Toda K, Eya K, Miyazaki K, Takewa Y, Takano H. Tandem operation of a turbo blood pump (BP-80-type centrifugal pump) to reduce hemolysis. Artif Organs 1996; 20(6): 572 4.
10.1111/j.1525-1594.1996.tb04483.x
PubMed Web of Science® Google Scholar
22 Olsen DB & Bramm G. Blood pump with a magnetically suspended impeller. Trans Am Soc Artif Intern Organs 1985; 31: 395 401.
CAS PubMed Google Scholar
23 Park CH, Nishimura K, Akamatsu T, Tsukiya T, Matsuad K, Ban T. A new magnetically suspended centrifugal pump: In vitro and preliminary in vivo assessment. Artif Organs 1996; 20(2): 128 31.
10.1111/j.1525-1594.1996.tb00714.x
CAS PubMed Web of Science® Google Scholar
24 Van Oeveren W. Biomaterials for rotary blood pumps. Artif Organs 1995; 19(7): 603 7.
10.1111/j.1525-1594.1995.tb02388.x
CAS PubMed Web of Science® Google Scholar

Citing Literature

Volume23, Issue8

August 1999

Pages 769-773

Blood Flow in a Continuous Flow Ventricular Assist Device

Abstract

References

Citing Literature

References

Information

About Wiley Online Library

Help & Support

Opportunities

Connect with Wiley

Blood Flow in a Continuous Flow Ventricular Assist Device

Abstract

References

Citing Literature

References

Related

Information