Volume 35, Issue 3 pp. 287-290

Viral aetiology of lower respiratory tract infection in young Malaysian children

PWK Chan,

PWK Chan

Departments of Paediatrics and,

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AYT Goh,

AYT Goh

Departments of Paediatrics and,

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KB Chua,

KB Chua

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

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NS Kharullah,

NS Kharullah

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

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PS Hooi,

PS Hooi

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

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PWK Chan,

PWK Chan

Departments of Paediatrics and,

Search for more papers by this author

AYT Goh,

AYT Goh

Departments of Paediatrics and,

Search for more papers by this author

KB Chua,

KB Chua

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

Search for more papers by this author

NS Kharullah,

NS Kharullah

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

Search for more papers by this author

PS Hooi,

PS Hooi

Medical Microbiology, University Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia

Search for more papers by this author

First published: 28 February 2002

https://doi.org/10.1046/j.1440-1754.1999.00359.x

Citations: 20

Dr PWK Chan Department of Paediatrics, University Hospital, 50603 Kuala Lumpur, Malaysia. Fax: 603 755 6114; email: [email protected]

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Abstract

Objective: To study the viral aetiology of lower respiratory tract infection (LRTI) in young Malaysian children.

Methodology: A retrospective review was performed of LRTI patients aged less than 24 months who were admitted to the University Malaya Medical Centre between 1982 and 1997. Respiratory viruses in their nasopharyngeal secretion were identified by indirect immunofluorescence, viral culture, or both.

Results: A total of 5691 children were included in the study. The mean age was 8.6 ± 6.6 months and the M:F ratio was 1.6:1. The most common diagnosis was pneumonia (52%) followed by bronchiolitis (45%) and croup (2%). Positive viral isolation rate was 22.0%. Respiratory syncytial virus (RSV) was the commonest virus isolated (84%), followed by parainfluenza virus (8%), influenza virus (6%) and adenovirus (2%). Patients with positive virus isolation were younger (7.8 ± 6.2 vs 8.7 ± 6.7 months, P = 0.0001) and were more likely to have bronchiolitis.

Conclusion: Young Malaysian children admitted with LRTI had a 22% viral isolation rate and RSV was the commonest virus isolated.

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Volume35, Issue3

June 1999

Pages 287-290

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