A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein
T. Kamesaki
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorM. Kumada
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorT. Omi
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorH. Okuda
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorS. Iwamoto
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorE. Kajii
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorT. Kamesaki
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorM. Kumada
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorT. Omi
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorH. Okuda
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorS. Iwamoto
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this authorE. Kajii
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi, Japan
Search for more papers by this author
References
- 1 Wagner FF, Gassner C, Muller TH, Schonitzer D, Schunter F, Flegel WA: Molecular basis of weak D phenotypes. Blood 1999; 93: 385 – 393
- 2 Wagner FF, Frohmajer A, Ladewig B, Eicher NI, Lonicer CB, Muller TH, Siegel MH, Flegel WA: Weak D alleles express distinct phenotypes. Blood 2000; 95: 2699 – 2708
- 3 Kamesaki T, Iwamoto S, Kumada M, Omi T, Okuda H, Tanaka M, Takahashi J, Obara K, Seno T, Tani Y, Kajii E: Molecular characterization of weak D phenotypes by site-directed mutagenesis and expression of mutant Rh-green fluorescence protein fusions in K562 cells. Vox Sang 2001; 81: 254 – 258
- 4 Wagner FF, Flegel WA :The RhesusBase. Ulm, DRK-Blutspendedienst Baden-Wuerttemberg 2001. Available at http://www.uni-ulm.de/fwagner/RH/RB