CONSENSUS CONFERENCE ON PLATELET TRANSFUSION, ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 27–28 NOVEMBER 1997: Synopsis of background papers
Norfolk, Ancliffe, Contreras, Hunt, Machin, Murphy, Williamson,
Williamson
University of Cambridge/National Blood Service, U.K.
Search for more papers by this author Norfolk, Ancliffe, Contreras, Hunt, Machin, Murphy, Williamson,
Williamson
University of Cambridge/National Blood Service, U.K.
Search for more papers by this authorDr Norfolk Department of Haematology, Leeds General Infirmary, Leeds LS1 3EX.

References
- 1 Alcorta, I., Pereira, A., Ordinas, A. (1996) Clinical and laboratory factors associated with platelet transfusions refractoriness: a case–control study. British Journal of Haematology, 93, 220 224.
- 2 Anderson, N.A., Gray, S., Copplestone, J.A., Chan, D.C., Hamon, M., Prentice, A.G., Johnson, S.A., Phillips, M., Van Waeg, G., Oakhill, A., Abeyasekera, S., Pamphilon, D.H. (1996) A prospective randomised study of three types of platelet concentrates in patients with haematological malignancy: corrected platelet count increments and frequency of non haemolytic febrile transfusion reactions. Transfusion Medicine, 6, 33 39.
- 3 Andrew, M., Castle, V., Mitchell, L. (1989) Modified bleeding time in the infant. American Journal of Hematology, 30, 190 191.
- 4 Aye, M.T., Palmers, D.S., Giulivi, A., Hashemi, S. (1995) Effect of filtration of platelet concentrates on the accumulation of cytokines and platelet release factors during storage. Transfusion, 35, 117 124.
- 5 Babcock, R. B., Dumper, C. W., Scharfman, W.B. (1976) Heparin induced thrombocytopenia. New England Journal of Medicine, 295, 237 239.
- 6 Bertolini, F. & Murphy, S. (1996) Biomedical Excellence for Safer Transfusion (BEST) Working Party of the International Society of Blood Transfusion. A multi-center inspection of the swirling phenomenon in platelet concentrates prepared in routine practice. Transfusion, 36, 128 132.
- 7 Beutler, E. (1993) Platelet transfusions: the 20,000/μl trigger. Blood, 81, 1411 1413.
- 8 Blachman, M.A., Ali, A.M., Richardson, H.L. (1994) Bacterial contamination of cellular blood components. Vox Sanguinis, 67, 25 34.
- 9 Blanchette, V.S., Kuhne, T., Hume, H., Hellman, J. (1995) Platelet transfusion therapy in newborn infants. Transfusion Medicine Reviews, 9, 215 230.
- 10 Bolton-Maggs, P.H.B. & Moon, I. (1997) Assessment of UK practice for management of acute childhood idiopathic thrombocytopenic purpura against published guidelines. Lancet, 350, 620 623.
- 11 Bordin, J.O., Heddle, N.M., Blajchman, M.A. (1994) Biologic effects of leukocytes present in transfused cellular blood products. Blood, 84, 1703 1721.
- 12 British Committee for Standards in Haematology (1992) Guidelines for platelet transfusion. Transfusion Medicine, 2, 311 318.
- 13 Carr, J.M., Kruskall, M.S., Kaye, J.A., Robinson, S.H. (1986) Efficacy of platelet transfusion in immune thrombocytopenia. American Journal of Medicine, 80, 1051 1054.
- 14 Erberst, M.E. & Berkowitz, L.R. (1994) Hemostasis in renal disease: pathophysiology and management. American Journal of Medicine, 96, 168 179.
- 15 Friedberg, R.C., Donnelly, F.F., Mintz, P.D. (1994) Independent roles for platelet cross-matching and HLA in the selection of platelets for alloimmunized patients. Transfusion, 34, 215 220.
- 16 Gaydos, L.A., Freireich, E.J., Mantel, N. (1962) The quantitative relation between platelet count and hemorrhage in patients with acute leukemia. New England Journal of Medicine, 266, 905 909.
- 17 Gmur, J., Burger, J., Schanz, U., Fehr, J., Schaffner, A. (1991) Safety of stringent prophylactic platelet transfusion policy for patients with acute leukaemia. Lancet, 338, 1223 1236.
- 18
Han, T.,
Stutzman, L.,
Cohen, E.,
Kim, U. (1966) Effect of platelet transfusion on haemorrhage in patients with acute leukaemia.
Cancer, 19, 1937 1942.
10.1002/1097-0142(196612)19:12<1937::AID-CNCR2820191221>3.0.CO;2-G CAS PubMed Web of Science® Google Scholar
- 19 Harker, L.A. (1986) Bleeding after cardiopulmonary bypass. New England Journal of Medicine, 314, 1446 1447.
- 20 Heddle, N.M., Luba Klama, R.T., Singer, J., Richards, C., Fedak, P., Walker, I., Kelton, J.G. (1994) The role of the plasma from platelet concentrates in transfusion reactions. New England Journal of Medicine, 331, 625 628.
- 21 Hersh, E.M., Bodey, G.P., Nies, B.A., Freireich, E.J. (1965) Causes of death in acute leukemia: a ten year study of 414 patients from 1954–1963. Journal of the American Medical Association, 193, 99 103.
- 22 Kallis, P., Tooze, J.A., Talbot, S., Cowans, D., Bevan, D.H., Treasure, T. (1994) Aprotinin inhibits fibrinolysis, improves platelet adhesion and reduces blood loss. Journal of Cardiothoracic Surgery, 8, 315 323.
- 23 Kelsey, H.C. (1992) An audit of the use of platelet concentrates in the prophylaxis of thrombocytopenic haemorrhage in a large haematology unit. Blood Coagulation and Fibrinolysis, 3, 647 649.
- 24 Levin, R.H. (1964) Handbook for Platelet Transfusion Therapy. National Cancer Institute, Special Publication, Bethesda, Maryland.
- 25 Lin, L., Cook, D.N., Wiesehahn, G.P., Alfonso, R., Behrman, B., Cimino, G.D., Corten, L., Damonte, P.B., Dikeman, R., Dupuis, K., Fang, Y.M., Hanson, C.V., Hearst, J.E., Lin, C.Y., Londe, H.F., Metchette, K., Nerio, A.T., Pu, J.T., Reames, A.A., Rheinschmidt, M., Tessman, J., Isaacs, S.T., Wollowitz, S., Corash, L. (1997) Photochemical inactivation of viruses and bacteria in platelet concentrates by the use of a novel psoralen and long-wavelength ultraviolet light. Transfusion, 37, 423 435.
- 26 Mallett, S.V. & Cox, D.J.A. (1992) Thromboclastography. British Journal of Anaesthesia, 69, 307 313.
- 27 Metcalfe, P., Williamson, L.M., Reutelingsperger, C.P.M., Swann, I., Ouwehand, W.H., Goodall, A.H. (1997) Activation during preparation of therapeutic platelets affects deterioration during storage: a comparative flow cytometry study of different production methods. British Journal of Haematology, 98, 86 95.
- 28 Mueller-Eckhardt, C. (1986) Post-transfusion purpura. British Journal of Haematology, 64, 419 424.
- 29 Murphy, M.F., Metcalfe, P., Ord, J., Lister, T.A., Waters, H.A. (1987) Disappearance of HLA and platelet-specific antibodies in acute leukaemia patients alloimmunized by multiple transfusions. British Journal of Haematology, 67, 255 260.
- 30 Murphy, M.F. & Waters, A.H. (1990) Platelet transfusions: the problem of refractoriness. Blood Reviews, 4, 16 24.
- 31 Murphy, M.F., Waters, A.H., Doughty, H.A., Hambley, H., Mibashan, R.S. (1994) Antenatal management of fetomaternal alloimmune thrombocytopenia: report of 15 affected pregnancies. Transfusion Medicine, 4, 281 292.
- 32 National Institutes of Health Consensus Conference: Platelet Transfusion Therapy (1987) Transfusion Medicine Reviews, 1, 195 200.
- 33 Norfolk, D.R. & Williamson, L.M. (1995) Leucodepletion of blood products by filtration. Blood Reviews, 9, 7 14.
- 34 Novotny, V.M.J., Van Doorn, R., Witfleet, M.C., Class, F.H., Brand, A. (1995) Occurrence of allogeneic HLA and non-HLA antibodies after transfusion of prestorage filtered platelets and red blood cells: a prospective study. Blood, 85, 1736 1741.
- 35 Pamphilon, D.H., Potter, M., Cutts, M., Meenaghan, M., Rogers, W., Slade, R.R., Saunders, J., Tandy, N.P., Fraser, I.D. (1990) Platelet concentrates irradiated with ultraviolet light retain satisfactory in vitro storage characteristics and in vivo survival. British Journal of Haematology, 75, 240 244.
- 36 Rebulla, P., Finazzi, G., Marangoni, F., Avvisati, G., Gugliotta, L., Tognoni, G., Barbui, T., Mandelli, F., Sirchia, G. (1997) A multicenter randomized study of the threshold for prophylactic platelet transfusions in adults with acute myeloid leukemia. New England Journal of Medicine, 337, 1870 1875.
- 37 Rinder, H.M., Murphy, M., Mitchell, J.G., Stocks, J., Ault, K.A., Hillman, R.S. (1991) Progressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion. Transfusion, 31, 409 414.
- 38 Rogers, R.P. & Levin, I.A. (1990) A critical reappraisal of the bleeding time. Seminars in Thrombosis and Hemostasis, 16, 1 20.
- 39 Simon, T.L., Akl, B.F., Murphy, W. (1984) Controlled trial of routine administration of platelet concentrates in cardiopulmonary bypass surgery. Annals of Thoracic Surgery, 37, 359 364.
- 40 Slichter, S.J. & Harker, L.A. (1978) Thrombocytopenia: mechanisms and management of defects in platelet function. Clinical Haematology, 7, 523 529.
- 41 Sloand, E.M., Yu, M., Klein, H.G. (1996) Comparison of random-donor platelet concentrates prepared from whole blood units and platelets prepared from single-donor apheresis collections. Transfusion, 36, 955 959.
- 42 Strauss, R.G. (1995) Clinical perspectives of platelet transfusion defining optimal dose. Journal of Clinical Apheresis, 10, 124 127.
- 43 Sweeney, J.D., Holme, S., Stromberg R.R. (1995) In vitro and in vivo effects of prestorage filtration of apheresis platelets. Transfusion, 35, 125 130.
- 44 The Trial to Reduce Alloimmunization to Platelets Study Group (1997) Leukocyte reduction and ultraviolet B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusions. New England Journal of Medicine, 337, 1861 1869.
- 45 Wagner, S.J., Friedman, L.I., Dodd, R.Y. (1994) Transfusion-associated bacterial sepsis. Clinical Microbiology Reviews, 7, 290 302.
- 46 Wallace, E.L., Churchill, W H., Surgenor, D.M., Cho, G., McGurk, S., Murphy, L. (1995) Collection and transfusion of blood and blood components in the United States (1992). Transfusion, 35, 802 812.
- 47 Williamson, L.M. & Warwick, R.M. (1995) Transfusion-associated graft versus host disease and its prevention. Blood Reviews, 9, 251 261.