Volume 64, Issue 7 e26421
SPECIAL REPORT

Staging Evaluation and Response Criteria Harmonization (SEARCH) for Childhood, Adolescent and Young Adult Hodgkin Lymphoma (CAYAHL): Methodology statement

Jamie E. Flerlage

Jamie E. Flerlage

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee

Search for more papers by this author
Kara M. Kelly

Kara M. Kelly

Roswell Park Cancer Institute, University of Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York

Search for more papers by this author
Auke Beishuizen

Auke Beishuizen

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands

Search for more papers by this author
Steve Cho

Steve Cho

Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin

Search for more papers by this author
Pedro A. De Alarcon

Pedro A. De Alarcon

University of Illinois College of Medicine, Peoria, Illinois

Search for more papers by this author
Ute Dieckmann

Ute Dieckmann

Klinik für Strahlenheilkunde, Universitätsklinik Freiburg, Freiburg, Germany

Search for more papers by this author
Richard A. Drachtman

Richard A. Drachtman

Division of Pediatric Hematology Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Search for more papers by this author
Bradford S. Hoppe

Bradford S. Hoppe

Department of Radiation Oncology, University of Florida, Gainesville, Florida

Search for more papers by this author
Scott C. Howard

Scott C. Howard

University of Memphis School of Health Studies, Memphis, Tennessee

Search for more papers by this author
Sue C. Kaste

Sue C. Kaste

Department of Diagnostic Imaging, University of Tennessee Health Sciences Center, Memphis, Tennessee

Search for more papers by this author
Regine Kluge

Regine Kluge

Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig, Germany

Search for more papers by this author
Lars Kurch

Lars Kurch

Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig, Germany

Search for more papers by this author
Judith Landman-Parker

Judith Landman-Parker

Department of Paediatric Haematology & Oncology, Hôpital Trousseau AP-HP & Université Pierre et Marie Curie, Paris, France

Search for more papers by this author
Jocelyn Lewis

Jocelyn Lewis

Division of Pediatric Hematology Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Search for more papers by this author
Michael P. Link

Michael P. Link

Division of Pediatric Hematology-Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California

Search for more papers by this author
Kathleen McCarten

Kathleen McCarten

Rhode Island Hospital/Warren Alpert Medical School at Brown University, Providence, Rhode Island

Search for more papers by this author
Angela Punnett

Angela Punnett

Division of Haematology/Oncology, Department of Paediatrics, SickKids Hospital and University of Toronto, Toronto, Canada

Search for more papers by this author
Dietrich Stoevesandt

Dietrich Stoevesandt

University Clinic Halle (Saale), Halle, Germany

Search for more papers by this author
Stephan D. Voss

Stephan D. Voss

Department of Radiology, Boston Children's Hospital Dana-Farber Cancer Institute, Boston, Massachusetts

Search for more papers by this author
William Hamish Wallace

William Hamish Wallace

Royal Hospital for Sick Children, Edinburgh, Scotland, UK

Search for more papers by this author
Christine Mauz-Körholz

Christine Mauz-Körholz

Department of Pädiatrische Hämatologie und Onkologie, Zentrum für Kinderheilkunde der Justus-Liebig-Universität Gießen, Gießen, Germany

Medical Faculty, Martin-Luther-University of Halle-Wittenberg, Halle, Germany

Christine Mauz-Korholz and Monika L. Metzger contributed equally to the writing of the manuscript.

Search for more papers by this author
Monika L. Metzger

Corresponding Author

Monika L. Metzger

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee

Christine Mauz-Korholz and Monika L. Metzger contributed equally to the writing of the manuscript.

Correspondence

Monika L. Metzger, Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38105.

Email: [email protected]

Search for more papers by this author
First published: 18 January 2017
Citations: 36

Abstract

International harmonization of staging evaluation and response criteria is needed for childhood, adolescence, and young adulthood Hodgkin lymphoma. Two Hodgkin lymphoma protocols from cooperative trials in Europe and North America were compared for areas in need of harmonization, and an evidence-based approach is currently underway to harmonize staging and response evaluations with a goal to enhance comparisons, expedite identification of effective therapies, and aid in the approval process for new agents by regulatory agencies.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.