Volume 64, Issue 7 e26381
REVIEW

The effect of maternal and infant factors on cord blood yield

Seyed Hadi Mousavi

Corresponding Author

Seyed Hadi Mousavi

Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran

Correspondence

Seyed Hadi Mousavi, Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran 14177-44361, Iran.

Email: [email protected]

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Saeid Abroun

Saeid Abroun

Department of Hematology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran

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Morteza Zarrabi

Morteza Zarrabi

Royan Stem Cell Technology Institute, Cord Blood Bank, Tehran, Iran

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Mona Ahmadipanah

Mona Ahmadipanah

Royan Stem Cell Technology Institute, Cord Blood Bank, Tehran, Iran

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First published: 01 December 2016
Citations: 6

Abstract

Umbilical cord blood (CB) can be used as an alternative hematopoietic stem cell source for transplantation in hematological malignancy and blood disorders. The success of transplantation is highly related to the levels of total nucleated cell and CD34+ cell counts. The evaluation of optimal conditions can decrease the rate of graft rejection due to low cell count and increases the quality of CB units (CBUs) in the blood bank and the success rate of engraftment. To this end, we review the maternal and infant parameters affecting the quality and quantity of CBUs.

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