Volume 63, Issue 7 pp. 1141-1143
HIGHLIGHT

Lidocaine Infusions and Other Options for Opioid-Resistant Pain Due to Pediatric Advanced Cancer

Charles Berde MD, PhD

Corresponding Author

Charles Berde MD, PhD

Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts

Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts

Correspondence to: Charles Berde, Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, 333 Longwood Ave 5th floor, Boston, MA 02115. E-mail: [email protected]

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Anjali Koka MD

Anjali Koka MD

Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts

Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts

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Carolina Donado-Rincon MD

Carolina Donado-Rincon MD

Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts

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First published: 15 April 2016
Citations: 11

Conflict of interest: Drs. Koka and Donado report no biomedical financial interests or potential conflicts of interest. Dr. Berde, his collaborators, and Boston Children's Hospital have issued patents on site 1 sodium channel blockers for prolonged duration local anesthesia. Boston Children's Hospital has established a collaboration with Proteus SA, a biotech company in Santiago, Chile, for development of neosaxitoxin, a site 1 sodium channel blocker, for prolonged duration local anesthesia. Boston Children's Hospital and Proteus have recently concluded a licensure and development agreement with Grunenthal GmbH, a pharma company based in Aachen, Germany. In the event of further development, Dr. Berde, his collaborators, and Boston Children's Hospital could receive milestone payments and royalties. Dr. Berde has received no equity or other payments from commercial entities for this work.

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