Volume 55, Issue 6 pp. 1198-1200

Brief Report

Multicentric castleman disease in a child with primary immunodeficiency^†

Jean-Philippe Drolet MD,

Jean-Philippe Drolet MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Marie-Astrid Lefebvre MD,

Marie-Astrid Lefebvre MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Chantal Bernard MD,

Chantal Bernard MD

Division of Pathology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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David Mitchell MD,

David Mitchell MD

Division of Hematology and Oncology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Christine McCusker MD,

Christine McCusker MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Bruce Mazer MD,

Corresponding Author

Bruce Mazer MD

[email protected]

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, 2300 Tupper St, Montreal, Quebec, Canada H3H 1P3.===Search for more papers by this author

Jean-Philippe Drolet MD,

Jean-Philippe Drolet MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Marie-Astrid Lefebvre MD,

Marie-Astrid Lefebvre MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Chantal Bernard MD,

Chantal Bernard MD

Division of Pathology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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David Mitchell MD,

David Mitchell MD

Division of Hematology and Oncology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Christine McCusker MD,

Christine McCusker MD

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

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Bruce Mazer MD,

Corresponding Author

Bruce Mazer MD

[email protected]

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada

Division of Allergy and Clinical Immunology, Montreal Children's Hospital, 2300 Tupper St, Montreal, Quebec, Canada H3H 1P3.===Search for more papers by this author

First published: 16 September 2010

https://doi.org/10.1002/pbc.22776

Citations: 4

^†

Conflict of interest: Nothing to report.

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Abstract

Multicentric Castleman disease is a rare lymphoproliferative disorder mostly seen in adults with HIV. It presents with fever and systemic symptoms and is extremely uncommon in children. We describe a novel case of multicentric Castleman disease associated with primary immunodeficiency (common variable immunodeficiency) and discuss pathophysiologic mechanisms and recent advances in understanding this disease. Pediatr Blood Cancer. 2010;55:1198–1200. © 2010 Wiley-Liss, Inc.

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Volume55, Issue6

1 December 2010

Pages 1198-1200

Multicentric castleman disease in a child with primary immunodeficiency^†

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Multicentric castleman disease in a child with primary immunodeficiency†

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Multicentric castleman disease in a child with primary immunodeficiency^†