Volume 51, Issue 6 pp. 812-813
Brief Report

Control of massive bleeding in dengue hemorrhagic fever with severe thrombocytopenia by use of intravenous anti-D globulin

Satya P. Yadav DCH, DNB

Corresponding Author

Satya P. Yadav DCH, DNB

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi, India

Consultant, Pediatric Hematology and Oncology Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi 110060, India.===Search for more papers by this author
Anupam Sachdeva DCH, MD

Anupam Sachdeva DCH, MD

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi, India

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Dhiren Gupta MD

Dhiren Gupta MD

Pediatric Intensive Care Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi, India

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Sunil D. Sharma MBBS, DCH

Sunil D. Sharma MBBS, DCH

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi, India

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Gaurav Kharya MBBS, DCH

Gaurav Kharya MBBS, DCH

Pediatric Hematology and Oncology Unit, Department of Pediatrics, Center For Child Health, Sir Ganga Ram Hospital, New Delhi, India

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First published: 09 October 2008
Citations: 8

Abstract

Dengue hemorrhagic fever (DHF) is a potentially lethal complication of mosquito borne viral disease, Dengue Fever. Thrombocytopenia is a constant finding in DHF/Dengue Shock Syndrome (DSS). We report two cases that fulfilled the WHO criteria of DSS: high fever, positive tourniquet test, severe thrombocytopenia (<10,000/mm3), hemo-concentration (Hematocrit increase >20%), hypotension and bleeding refractory to routine therapeutic measures, who showed dramatic improvement after receiving Intravenous Anti-D globulin (IV anti-D). Pediatr Blood Cancer 2008;51:812–813. © 2008 Wiley-Liss, Inc.

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