Urologic Chronic Pelvic Pain Syndrome: A Scoping Review of Syndrome-Specific Instruments
Arya Catna
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorVictoria L. Brown
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Search for more papers by this authorClaire Gwak
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorDeeksha Kanagarag
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorMadeline Meyer
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorSrinitya Rapolu
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorRatna Pakpahan
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorLauren Yaeger
Washington University School of Medicine, Bernard Becker Medical Library, St. Louis, Missouri, USA
Search for more papers by this authorJames W. Griffith
Departments of Obstetrics and Gynecology, and Psychiatry and Behavioral Neuroscience, The University of Chicago Medicine, Chicago, Illinois, USA
Search for more papers by this authorAimee S. James
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorH. Henry Lai
Department of Surgery; and the Department of Anesthesiology, Washington University School of Medicine, Division of Urological Surgery, St. Louis, Missouri, USA
Search for more papers by this authorJerry L. Lowder
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Search for more papers by this authorCorresponding Author
Siobhan Sutcliffe
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Correspondence: Siobhan Sutcliffe ([email protected])
Search for more papers by this authorArya Catna
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorVictoria L. Brown
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Search for more papers by this authorClaire Gwak
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorDeeksha Kanagarag
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorMadeline Meyer
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorSrinitya Rapolu
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorRatna Pakpahan
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorLauren Yaeger
Washington University School of Medicine, Bernard Becker Medical Library, St. Louis, Missouri, USA
Search for more papers by this authorJames W. Griffith
Departments of Obstetrics and Gynecology, and Psychiatry and Behavioral Neuroscience, The University of Chicago Medicine, Chicago, Illinois, USA
Search for more papers by this authorAimee S. James
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Search for more papers by this authorH. Henry Lai
Department of Surgery; and the Department of Anesthesiology, Washington University School of Medicine, Division of Urological Surgery, St. Louis, Missouri, USA
Search for more papers by this authorJerry L. Lowder
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Search for more papers by this authorCorresponding Author
Siobhan Sutcliffe
Department of Surgery, Washington University School of Medicine, Division of Public Health Sciences, St. Louis, Missouri, USA
Department of Obstetrics and Gynecology, Washington University School of Medicine, Division of Urogynecology and Reconstructive Pelvic Surgery, St. Louis, Missouri, USA
Correspondence: Siobhan Sutcliffe ([email protected])
Search for more papers by this authorClaire Gwak, Deeksha Kanagarag, Madeline Meyer, and Srinitya Rapolu contributed equally to this study.
ABSTRACT
Objective
To facilitate research on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) symptom variability or flares, we reviewed the published literature to document existing data collection instruments (e.g., questionnaires and diaries), and to identify those relevant for flare research.
Methods
Seven databases were searched systematically for articles describing the development of instruments: (1) specific for IC/BPS, CP/CPPS, or both; and (2) intended for use by investigators beyond the development team. In total, 1216 abstracts and 79 full-text articles were reviewed, and data were extracted in duplicate.
Results
We identified 17 instruments, 11 for IC/BPS, 5 for CP/CPPS, and 1 for both. In total, 13 instruments (12 questionnaires and 1 electronic diary) assessed symptoms for diagnostic, symptom evaluation, and/or symptom monitoring purposes, and included items assessing the presence, location, intensity (mostly typical intensity), and/or amount of time experienced pelvic pain and/or urinary symptoms. No instruments included items related to symptom variability or flares.
Conclusion
In addition to describing existing instruments for future urologic CPPS research, our review identified a lack of validated instruments for flares. Future studies should address this gap to facilitate rigorous research on this understudied topic.
Conflicts of Interest
The authors declare no conflicts of interest.
Open Research
Data Availability Statement
All extracted data are presented in Tables 1–4.
Supporting Information
| Filename | Description |
|---|---|
| nau70087-sup-0001-SupMat.docx17.7 KB | UCPPS symptom variability systematic review manuscript - draft 5 May 11, 2025 - supplemental. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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