Letter to the Editor
Is sarcopenia driven by motor neuron/unit loss? An unresolved question
W. David Arnold MD,
W. David Arnold MD
Department of Neurology, The Ohio State University, Columbus, Ohio, USA
Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, Ohio, USA
Department of Neuroscience, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this author Brian C. Clark PhD,
Brian C. Clark PhD
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, Ohio, USA
Department of Biomedical Science Ohio University, Athens, Ohio, USA
Department of Geriatric Medicine, Ohio University, Athens, Ohio, USA
Search for more papers by this author
W. David Arnold MD,
W. David Arnold MD
Department of Neurology, The Ohio State University, Columbus, Ohio, USA
Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, Ohio, USA
Department of Neuroscience, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this author Brian C. Clark PhD,
Brian C. Clark PhD
Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, Ohio, USA
Department of Biomedical Science Ohio University, Athens, Ohio, USA
Department of Geriatric Medicine, Ohio University, Athens, Ohio, USA
Search for more papers by this author
First published: 22 March 2017
No abstract is available for this article.
- 1
Gilmore KJ,
Morat T,
Doherty TJ,
Rice CL. Motor unit number estimation and neuromuscular fidelity in 3 stages of sarcopenia. Muscle Nerve. Epub 2016/09/01. doi: 10.1002/mus.25394.
- 2
Tomlinson BE,
Irving D. The numbers of limb motor neurons in the human lumbosacral cord throughout life. J Neurol Sci 1977; 34: 213–219.
- 3
Rich MM,
Wang X,
Cope TC,
Pinter MJ. Reduced neuromuscular quantal content with normal synaptic release time course and depression in canine motor neuron disease. J Neurophysiol 2002; 88: 3305–3314.
- 4
Bromberg MB,
Abrams JL. Sources of error in the spike-triggered averaging method of motor unit number estimation (MUNE). Muscle Nerve 1995; 18: 1139–1146.
- 5
Shefner JM,
Cudkowicz ME,
Zhang H,
Schoenfeld D,
Jillapalli D. The use of statistical MUNE in a multicenter clinical trial. Muscle Nerve 2004; 30: 463–469.