Volume 127, Issue 10 pp. 2247-2251
Head and Neck

Postoperative complications of total laryngectomy in diabetic patients

Andrey Filimonov PharmD

Andrey Filimonov PharmD

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Jacob S. Brady BA

Jacob S. Brady BA

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Aparna Govindan BA

Aparna Govindan BA

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Aziz Merchant MD

Aziz Merchant MD

Department of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Jean Anderson Eloy MD, FACS

Jean Anderson Eloy MD, FACS

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Department of Neurological Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Department of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Soly Baredes MD, FACS

Soly Baredes MD, FACS

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Center for Skull Base and Pituitary Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

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Richard Chan Woo Park MD, FACS

Corresponding Author

Richard Chan Woo Park MD, FACS

Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Send correspondence to Richard Chan Woo Park, MD, Department of Otolaryngology–Head and Neck Surgery, Rutgers New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ 07103. E-mail: [email protected]Search for more papers by this author
First published: 17 March 2017
Citations: 12

The authors have no funding, financial relationships, or conflicts of interest to disclose.

Abstract

Objectives/Hypothesis

Analyze postoperative complications of total laryngectomies (TL) in patients with diabetes mellitus and apply these data toward preoperative management of diabetic patients undergoing TL.

Study Design

Retrospective analysis of surgical outcomes database

Methods

The American College of Surgeons National Surgical Quality Improvement Program database was queried for TL performed between 2005 and 2013. Comparison of demographics, preoperative comorbidities, and postoperative outcomes in a diabetic versus a nondiabetic cohort was conducted using SPSS software. Equal distribution of demographics and preoperative comorbidities was ensured between the diabetic and nondiabetic cohorts using a propensity-matching algorithm.

Results

Following propensity matching there were 495 TL patients included in this study. Among these, 110 (22.2%) were diabetic and 385 (77.8%) were nondiabetic. The only comorbidities associated with the diabetic cohort after matching were obesity, previous percutaneous coronary intervention, and hypertension. The rates of superficial surgical site infections were higher in the diabetic patient cohort (10.9% vs. 4.7%, P = .022). There were no significant differences in unplanned readmission (12.7% vs. 9.1%, P = .260), reoperation (14.3% vs. 15.1%, P = .864), and mortality (1.8% vs. 2.6%, P = 1.000) between the diabetic and the nondiabetic groups. Multivariate regression utilizing preoperative variables not accounted for by propensity matching showed that superficial surgical site infections were still higher in the diabetes cohort (odds ratio: 3.371, P = .021).

Conclusions

Diabetic patients undergoing TL showed an increased incidence of superficial surgical site infections postoperatively. There were no other significant differences in readmission, reoperation, and mortality.

Level of Evidence

4 Laryngoscope, 127:2247–2251, 2017

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