Volume 121, Issue 8 pp. 1668-1674

Head and Neck

Transoral robotic resection and reconstruction for head and neck cancer^†

Eric M. Genden MD,

Corresponding Author

Eric M. Genden MD

[email protected]

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Immunology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

Department of Otolaryngology–Head and Neck Surgery, Professor of Neurosurgery, Director, Head and Neck Cancer Center, The Mount Sinai Medical Center, Box 1189, 5 East 98th Street, 8th Floor, New York, NY 10029Search for more papers by this author

Tamar Kotz MS, CCC-SLP,

Tamar Kotz MS, CCC-SLP

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

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Charles C. L. Tong MS,

Charles C. L. Tong MS

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Radiation Oncology New York, New York, U.S.A.

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Claris Smith BA,

Claris Smith BA

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

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Andrew G. Sikora MD, PhD,

Andrew G. Sikora MD, PhD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Dermatology New York, New York, U.S.A.

Immunology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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Marita S. Teng MD,

Marita S. Teng MD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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Stuart H. Packer MD,

Stuart H. Packer MD

Medical Oncology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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William L. Lawson MD,

William L. Lawson MD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

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Johnny Kao MD,

Johnny Kao MD

Radiation Oncology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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Eric M. Genden MD,

Corresponding Author

Eric M. Genden MD

[email protected]

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Immunology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

Tamar Kotz MS, CCC-SLP,

Tamar Kotz MS, CCC-SLP

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Search for more papers by this author

Charles C. L. Tong MS,

Charles C. L. Tong MS

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Radiation Oncology New York, New York, U.S.A.

Search for more papers by this author

Claris Smith BA,

Claris Smith BA

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Search for more papers by this author

Andrew G. Sikora MD, PhD,

Andrew G. Sikora MD, PhD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Dermatology New York, New York, U.S.A.

Immunology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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Marita S. Teng MD,

Marita S. Teng MD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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Stuart H. Packer MD,

Stuart H. Packer MD

Medical Oncology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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William L. Lawson MD,

William L. Lawson MD

Mount Sinai School of Medicine Departments of Otolaryngology–Head and Neck Surgery, New York, New York, U.S.A.

Search for more papers by this author

Johnny Kao MD,

Johnny Kao MD

Radiation Oncology New York, New York, U.S.A.

Tisch Cancer Institute, New York, New York, U.S.A

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First published: 25 July 2011

https://doi.org/10.1002/lary.21845

Citations: 131

^†

The authors have no funding, financial relationships, or conflicts of interest to disclose.

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Abstract

Objectives/Hypothesis:

To evaluate the patterns of failure, survival, and functional outcomes for patients treated with transoral robotic surgery (TORS) and compare these results with those from a cohort of patients treated with concurrent chemoradiation (CRT).

Study Design:

Prospective non-randomized case control study.

Methods:

Between April 2007 and April 2009, 30 patients with head and neck squamous cell carcinoma were treated with primary TORS and adjuvant therapy as indicated on an institutional review board–approved protocol. Patients were evaluated before treatment, after treatment, and at subsequent 3-month intervals after completing treatment to determine their disease and head and neck–specific functional status using the Performance Status Scale for Head and Neck Cancer and the Functional Oral Intake Score (FOIS). Functional scores were compared to a matched group of head and neck patients treated with primary CRT.

Results:

The TORS patient population included 73% stage III-IV and 23% nonsmokers. The median follow-up was 20.4 months (range, 12.8–39.6 months). The 18-month locoregional control, distant control, disease-free survival, and overall survival were 91%, 93%, 78%, and 90%, respectively. Compared to the primary CRT group, TORS was associated with better short-term eating ability (72 vs. 43, P = .008), diet (43 vs. 25, P = .01), and FOIS (5.5 vs. 3.3, P < .001) at 2 weeks after completion of treatment. In contrast to TORS patients who returned to baseline, the CRT group continued to have decreased diet (P = .03) and FOIS (P = .02) at 12 months.

Conclusions:

Our early experience in treating selected head and neck cancers with TORS is associated with excellent oncologic and functional outcomes that compare favorably to primary CRT.

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Citing Literature

Volume121, Issue8

August 2011

Pages 1668-1674

Transoral robotic resection and reconstruction for head and neck cancer^†

Abstract

Objectives/Hypothesis:

Study Design:

Methods:

Results:

Conclusions:

BIBLIOGRAPHY

Citing Literature

References

Information

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Transoral robotic resection and reconstruction for head and neck cancer†

Abstract

Objectives/Hypothesis:

Study Design:

Methods:

Results:

Conclusions:

BIBLIOGRAPHY

Citing Literature

References

Related

Information

Transoral robotic resection and reconstruction for head and neck cancer^†