Editorial
Editorial for “Noninvasive Assessment of MGMT Promoter Methylation Status in World Health Organization Grade II-IV Glioma Using Histogram Analysis of Inflow-Based Vascular-Space Occupancy Combined with Structural MR Imaging”
Letterio S. Politi MD,
Corresponding Author
Letterio S. Politi MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Neuroradiology Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Federico Pessina MD,
Federico Pessina MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Matteo Simonelli MD,
Matteo Simonelli MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Oncology Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Pierina Navarria MD,
Pierina Navarria MD
Radiotherapy Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author
Letterio S. Politi MD,
Corresponding Author
Letterio S. Politi MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Neuroradiology Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Federico Pessina MD,
Federico Pessina MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Matteo Simonelli MD,
Matteo Simonelli MD
Department of Biomedical Sciences, Humanitas University, Milan, Italy
Oncology Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author Pierina Navarria MD,
Pierina Navarria MD
Radiotherapy Department, IRCCS Humanitas Research Hospital, Milan, Italy
Search for more papers by this author
First published: 12 March 2021
No abstract is available for this article.
References
- 1Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-1354.
- 2Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization classification of tumors of the central nervous system: A summary. Acta Neuropathol 2016; 131: 803-820.
- 3Moon WJ, Choi JW, Roh HG, Lim SD, Koh YC. Imaging parameters of high-grade gliomas in relation to the MGMT promoter methylation status: The CT, diffusion tensor imaging, and perfusion MR imaging. Neuroradiology 2012; 54: 555-563.
- 4Jiang S, Rui Q, Wang Y, et al. Discriminating MGMT promoter methylation status in patients with glioblastoma employing amide proton transfer-weighted MRI metrics. Eur Radiol 2018; 28: 2115-2123.
- 5Ryoo I, Choi SH, Kim J-H, et al. Cerebral blood volume calculated by dynamic susceptibility contrast-enhanced perfusion MR imaging: Preliminary correlation study with glioblastoma genetic profiles. PLoS One 2013; 8:e71704.
- 6Qin JB, Zhang H, Wang XC, Tan Y, Wu XF. Combination value of diffusion-weighted imaging and dynamic susceptibility contrast-enhanced MRI in astrocytoma grading and correlation with GFAP, topoisomerase IIα and MGMT. Oncol Lett 2019; 18: 2763-2770.
- 7Chang P, Grinband J, Weinberg BD, et al. Deep-learning convolutional neural networks accurately classify genetic mutations in gliomas. Am J Neuroradiol 2018; 39: 1201-1207.
- 8He et al. Noninvasive assessment of MGMT promoter methylation status in World Health Organization grade II-IV glioma using histogram analysis of inflow-based vascular-space occupancy combined with structural MR imaging. J Magn Reson Imaging 2021.
- 9Hua J, Qin Q, Donahue MJ, Zhou J, Pekar JJ, Van Zijl PCM. Inflow-based vascular-space-occupancy (iVASO) MRI. Magn Reson Med 2011; 66: 40-56.