Frontiers in musculoskeletal MRI: Articular cartilage
Corresponding Author
J. Bruce Kneeland MD
Department of Radiology, University Of Pennsylvania Health System, Philadelphia, Pennsylvania
Department of Radiology, Pennsylvania Hospital, Philadelphia, Pennsylvania
Dept of Radiology, Pennsylvania Hospital, 800 Spruce St, Philadelphia, PA 19107Search for more papers by this authorRavinder Reddy PhD
Department of Radiology, University Of Pennsylvania Health System, Philadelphia, Pennsylvania
Metabolic Magnetic Resonance Research and Computation Center, Department of Radiology, Pennsylvania Hospital, Philadelphia, Pennsylvania
Search for more papers by this authorCorresponding Author
J. Bruce Kneeland MD
Department of Radiology, University Of Pennsylvania Health System, Philadelphia, Pennsylvania
Department of Radiology, Pennsylvania Hospital, Philadelphia, Pennsylvania
Dept of Radiology, Pennsylvania Hospital, 800 Spruce St, Philadelphia, PA 19107Search for more papers by this authorRavinder Reddy PhD
Department of Radiology, University Of Pennsylvania Health System, Philadelphia, Pennsylvania
Metabolic Magnetic Resonance Research and Computation Center, Department of Radiology, Pennsylvania Hospital, Philadelphia, Pennsylvania
Search for more papers by this authorAbstract
The techniques and uses of MRI in current clinical practice, primarily as a means to detect morphologic abnormalities, are reviewed. Ongoing development of techniques that can improve morphologic assessment including techniques to increase spatial and contrast resolution is discussed, as are methods to measure cartilage volumes and thickness. Finally, several of the more widely studied techniques used to probe loss of the macromolecular structure of cartilage prior to the development of macroscopic defects are presented and compared. J. Magn. Reson. Imaging 2007. © 2007 Wiley-Liss, Inc.
REFERENCES
- 1 Mankin HJ, Mow VC, Buckwalter JA, et al. Form and function of articular cartilage. In: SR Simon, editor. Orthopaedic basic science. Rosemont, IL: AAOS Press; 1994. p 3–8.
- 2 Goodwin DW, Wadghiri YZ, Zhu H, et al. Macroscopic structure of articular cartilage of the tibial plateau: influence of a characteristic matrix architecture on MRI appearance. AJR Am J Roentgenol 2004; 182: 311–318.
- 3 Recht MP, Goodwin DW, Winalski CS, White LM. MRI of articular cartilage: revisiting current status and future directions, AJR Am J Roentgenol 2005; 185: 899–914.
- 4 Hull RG, Rennie JAN, Eastmond CJ, et al. Nuclear magnetic resonance (NMR) tomographic imaging for popliteal cysts in rheumatoid arthritis. Ann Rheum Dis 1984; 43: 56–59.
- 5 Disler DG, McCauley TR, Wirth CR, Fuchs MD. Detection of knee hyaline cartilage defects using fat-suppressed, three-dimensional spoiled gradient echo imaging. AJR Am J Roentgenol 1995; 165: 377–382.
- 6 Bredella MA, Tirman PJ, Peterfy CG, et al. Accuracy of T2-weighted fast spin-echo MR imaging with fat saturation in detecting cartilage defects in the knee. AJR Am J Roentgenol 1999; 172: 1073–1080.
- 7 McCauley TR, Kier R, Lynch KJ, Jokl P. Chondromalacia patellae: diagnosis with MR imaging. AJR Am J Roentgenol 1992; 158: 101–105.
- 8
Hargreaves BA,
Gold GE,
Lang PE, et al.
MR imaging of articular cartilage using driven equilibrium.
Magn Reson Med
1999;
42:
695–703.
10.1002/(SICI)1522-2594(199910)42:4<695::AID-MRM11>3.0.CO;2-Z CAS PubMed Web of Science® Google Scholar
- 9 Hargreaves BA, Gold GE, Beaulieu CF, et al. Comparison of new sequences for high-resolution cartilage imaging. Magn Reson Med 2003; 180: 357–362.
- 10 Vasanawala SS, Pauly JM, Nishimura DG, et al. MR imaging of knee cartilage with FEMR. Skeletal Radiol 2002; 31: 574–580.
- 11 Eckstein F, Westhoff J, Sittek H, et al. In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with MR imaging. AJR Am J Roentgenol 1998; 170: 593–597.
- 12 Peterfy CG, van Dijke CG, Lu Y, et al. Quantification of the volume of the articular cartilage of the metacarpophalangeal joints of the hand. AJR Am J Roentgenol 1995; 165: 371–375.
- 13 Williams A, Gillis A, McKenzie C, et al. Glycosaminoglycan distribution in cartilage as determined by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). AJR Am J Roentgenol 2004; 182: 167–172.
- 14 Bashir A, Gray ML, Burstein D. Gd-DTPA as a measure of cartilage degradation. Magn Reson Med 1996; 36: 665–673.
- 15 Duvvuri U, Reddy R, Patel S, et al. T1ρ-relaxation in articular cartilage: effects of enzymatic degradation. Magn Reson Med 1997; 38: 863–867.
- 16 Duvveri U, Goldberg AD, Kranz JK, et al. Water magnetic relaxation dispersion in biological systems: the contribution of proton exchange and implications for the noninvasive detection of cartilage degradation. Proc Natl Acad Sci USA 2001; 98: 12479–12484.
- 17 Duvvuri U, Reddy R, Patel S, et al. T1ρ-relaxation in articular cartilage: effects of enzymatic degradation. Magn Reson Med 1997; 38: 863–867.
- 18 Wheaton AJ, Casey FL, Gougoutas AJ, et al. Correlation of T1ρ with fixed charged density in cartilage. J Magn Reson Imaging 2004; 20: 519–525.
- 19 Wheaton AJ, Borthakur A, Corbo M, et al. Method for reduced SAR T1ρ-weighted MRI. Magn Reson Med 2004; 51: 1096–1102.
- 20 Wheaton AJ, Borthakur A, Charagundla SR, Reddy R. Pulse sequence for multi-slice T1ρ-weighted MRI. Magn Reson Med 2004; 51: 362–369.
- 21 Dardzinski BJ, Mosher TJ, Li S, et al. Spatial variation of T2 in human articular cartilage. Radiology 1997; 205: 546–550.
- 22 Mosher TJ, Dardzinski BJ, Smith MB. Human articular cartilage: influence of aging and early symptomatic degeneration on the spatial variation of T2. Radiology 2000; 214: 259–266.
- 23 Regatte RR, Akella SVS, Borthakur A, et al. Proteoglycan depletion-induced changes in transverse relaxation maps of cartilage: comparison of T2 and T1ρ. Acad Radiol 2002; 9: 1388–1394.
- 24 Watrin-Pinzano A, Ruaud J-P, Olivier P, et al. Effect of proteoglycans depletion on T2 mapping in rat patellar cartilage. Radiology 2005; 234: 162–170.
- 25 Xia Y, Moody JB, Burton-Wurster N, Lust G. Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage. Osteoarthritis Cartilage 2001; 9: 393–406.
- 26 Van Breuseghem I, Bosmans HTC, Elst LV, et al. T2 mapping of human cartilage with turbo mixed MRI at 1.5 T. Radiology 2004; 233: 609–614.