Degradation behavior of biodegradable Fe35Mn alloy stents
N. B. Sing
IJN-UTM Cardiovascular Engineering Center & Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Search for more papers by this authorA. Mostavan
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Search for more papers by this authorE. Hamzah
Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Search for more papers by this authorCorresponding Author
D. Mantovani
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Correspondence to: H. Hermawan, (e-mail: [email protected]) or Diego Mantovani (e-mail: [email protected])Search for more papers by this authorCorresponding Author
H. Hermawan
IJN-UTM Cardiovascular Engineering Center & Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Correspondence to: H. Hermawan, (e-mail: [email protected]) or Diego Mantovani (e-mail: [email protected])Search for more papers by this authorN. B. Sing
IJN-UTM Cardiovascular Engineering Center & Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Search for more papers by this authorA. Mostavan
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Search for more papers by this authorE. Hamzah
Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Search for more papers by this authorCorresponding Author
D. Mantovani
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Correspondence to: H. Hermawan, (e-mail: [email protected]) or Diego Mantovani (e-mail: [email protected])Search for more papers by this authorCorresponding Author
H. Hermawan
IJN-UTM Cardiovascular Engineering Center & Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru, Malaysia
Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Mining, Metallurgical and Materials Engineering & CHU de Québec Research Center, Laval University, Quebec City, Canada
Correspondence to: H. Hermawan, (e-mail: [email protected]) or Diego Mantovani (e-mail: [email protected])Search for more papers by this authorAbstract
This article reports a degradation study that was done on stent prototypes made of biodegradable Fe35Mn alloy in a simulated human coronary arterial condition. The stent degradation was observed for a short-term period from 0.5 to 168 h, which simulates the early period of stenting procedure. Potentiodynamic polarization and electrochemical impedance spectroscopy were used to quantify degradation rate and surface property of the stents. Results showed that signs of degradation were visible on both crimped and expanded stents after 1 h of test, mostly located on the stent's curvatures. The degradation rate of stent was higher compared to that of the original alloy, indicating the surface altering effect of stent fabrication processing to degradation. A single oxide layer was formed and detected as a porous structure with capacitive behavior. Expanded stents exhibited lower polarization resistance compared to the nonexpanded ones, indicating the cold work effect of expansion procedure to degradation. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 572–577, 2015.
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