Short Report
Hepatitis C infection is not associated with systemic HIV-associated non-hodgkin's lymphoma: A cohort study
Laura Waters,
Justin Stebbing,
Sundhiya Mandalia,
Anne Marie Young,
Mark Nelson,
Brian Gazzard,
Mark Bower,
Laura Waters
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorJustin Stebbing
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorSundhiya Mandalia
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorAnne Marie Young
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorMark Nelson
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorBrian Gazzard
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorCorresponding Author
Mark Bower
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Fax: +44-208-746-8863
Department of Oncology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UKSearch for more papers by this authorLaura Waters,
Justin Stebbing,
Sundhiya Mandalia,
Anne Marie Young,
Mark Nelson,
Brian Gazzard,
Mark Bower,
Laura Waters
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorJustin Stebbing
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorSundhiya Mandalia
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorAnne Marie Young
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorMark Nelson
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorBrian Gazzard
Department of HIV Medicine, The Chelsea and Westminster Hospital, London, United Kingdom
Search for more papers by this authorCorresponding Author
Mark Bower
Department of Oncology, The Chelsea and Westminster Hospital, London, United Kingdom
Fax: +44-208-746-8863
Department of Oncology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UKSearch for more papers by this authorAbstract
Immunosuppression induced by the human immunodeficiency virus (HIV) increases the risk of developing non-Hodgkin's lymphoma (NHL). As the hepatitis C virus (HCV) has been implicated in the development of B cell lymphomas, we compared the incidence of systemic NHL during HIV infection compared to HIV and HCV co-infection. Of 5,832 individuals studied during the era of highly active anti-retroviral therapy (HAART), 102 patients were diagnosed with systemic NHL. The incidence of systemic NHL was 6.9 of 104 patient years during HIV infection compared to 7.1 of 104 patient years during HIV alone (p = 0.9). In this immunocompromised patient population, there was no association between HCV infection and an increased risk of lymphoma. © 2005 Wiley-Liss, Inc.
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