ORIGINAL ARTICLE
Effect of radiotherapy on the chemical composition of root dentin
Lívia Bueno Campi MSc,
Fabiane Carneiro Lopes PhD,
Luís Eduardo Silva Soares PhD,
Alexandra Mussolino de Queiroz PhD,
Harley Francisco de Oliveira PhD,
Paulo César Saquy PhD,
Manoel Damião de Sousa-Neto PhD,
Lívia Bueno Campi MSc
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorFabiane Carneiro Lopes PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorLuís Eduardo Silva Soares PhD
Laboratory of Dentistry and Applied Materials (LDAM), Research and Development Institute (IP&D), Universidade do Vale do Paraíba, Univap, São José dos Campos, São Paulo, Brazil
Search for more papers by this authorAlexandra Mussolino de Queiroz PhD
Department Children's Clinic, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorHarley Francisco de Oliveira PhD
Medical Clinic Department, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorPaulo César Saquy PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorCorresponding Author
Manoel Damião de Sousa-Neto PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Correspondence
Manoel D. Sousa Neto, Associate Professor, Department of Restorative Dentistry, School of Denistry of Ribeirão Preto, University of São Paulo, Rua Célia de Oliveira Meirelles 350, 14024-070, Ribeirão Preto, São Paulo, Brasil.
Email: [email protected]
Search for more papers by this authorLívia Bueno Campi MSc,
Fabiane Carneiro Lopes PhD,
Luís Eduardo Silva Soares PhD,
Alexandra Mussolino de Queiroz PhD,
Harley Francisco de Oliveira PhD,
Paulo César Saquy PhD,
Manoel Damião de Sousa-Neto PhD,
Lívia Bueno Campi MSc
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorFabiane Carneiro Lopes PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorLuís Eduardo Silva Soares PhD
Laboratory of Dentistry and Applied Materials (LDAM), Research and Development Institute (IP&D), Universidade do Vale do Paraíba, Univap, São José dos Campos, São Paulo, Brazil
Search for more papers by this authorAlexandra Mussolino de Queiroz PhD
Department Children's Clinic, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorHarley Francisco de Oliveira PhD
Medical Clinic Department, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorPaulo César Saquy PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Search for more papers by this authorCorresponding Author
Manoel Damião de Sousa-Neto PhD
Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
Correspondence
Manoel D. Sousa Neto, Associate Professor, Department of Restorative Dentistry, School of Denistry of Ribeirão Preto, University of São Paulo, Rua Célia de Oliveira Meirelles 350, 14024-070, Ribeirão Preto, São Paulo, Brasil.
Email: [email protected]
Search for more papers by this authorAbstract
Background
The radiotherapy can directly affect the bond strength of the adhesive materials, interfering in the prognosis of restorative treatments, which may be caused by chemical changes in dentin structure.
Methods
Twenty inferior homologues premolars were distributed in 2 groups (in vitro study) (n = 10): nonirradiated and irradiated. The specimens were submitted to the analysis of phosphate (ν1PO43−;ν2PO43−;ν4PO43−), carbonate (ν3CO32−), amide I, CH2, amide III, and amide I/III ratio by confocal Raman spectroscopy. Data were submitted to statistical analysis (T test, P < .05).
Results
In intracanal dentin, the irradiated group had lower ν4PO43− values (1.23 ± 0.06) compared to nonirradiated group (1.40 ± 0.18) (P < .05), with no difference for ν1PO43− and ν2PO43 peaks (P > .05). The irradiated (1.56 ± 0.06) had lower carbonate, amide III (1.05 ± 0.19), and amide I/III ratio values (0.19 ± 0.06) compared to nonirradiated group (1.42 ± 0.10, 1.28 ± 0.24, and 0.31 ± 0.10, respectively) (P < .05). For medium dentin irradiated group (1.30 ± 0.12) had lower phosphate values compared to nonirradiated group (1.48 ± 0.22) (P < .05). In cementum, there was no statistical difference between the groups.
Conclusion
The radiotherapy was able to cause changes in ν4PO43−, carbonate, and amide III peaks of root dentin.
CONFLICT OF INTEREST
None.
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