Original Article

Altered tissue electrical properties in squamous cell carcinoma in head and neck tumors: Preliminary observations^†

Corresponding Author

Teresa Małecka–Massalska MD, PhD

[email protected]

Physiology Department, Medical University of Lublin, Poland

Physiology Department, Medical University of Lublin, Radziwiłłowska 11 Str., 20-080 Lublin, PolandSearch for more papers by this author

Agata Smolen PhD,

Agata Smolen PhD

Department of Mathematics and Biostatistics, Medical University of Lublin, Poland

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Kamal Morshed MD, PhD,

Kamal Morshed MD, PhD

Otolaryngology Department, Head and Neck Oncology, Medical University of Lublin, Poland

Authorship: Teresa Małecka–Massalska was the main author of the manuscript and participated in the conception, design, data collection, data analysis, data interpretation, and writing. Agata Smolen assisted with the statistical analysis and data interpretation. Kamal Morshed participated in data collection, data interpretation, and writing.

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Teresa Małecka–Massalska MD, PhD,

Corresponding Author

Teresa Małecka–Massalska MD, PhD

[email protected]

Physiology Department, Medical University of Lublin, Poland

Physiology Department, Medical University of Lublin, Radziwiłłowska 11 Str., 20-080 Lublin, PolandSearch for more papers by this author

Agata Smolen PhD,

Agata Smolen PhD

Department of Mathematics and Biostatistics, Medical University of Lublin, Poland

Search for more papers by this author

Kamal Morshed MD, PhD,

Kamal Morshed MD, PhD

Otolaryngology Department, Head and Neck Oncology, Medical University of Lublin, Poland

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First published: 01 August 2012

https://doi.org/10.1002/hed.23091

Citations: 13

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Abstract

Background

The purpose of this study was to investigate tissue electrical properties in patients with head and neck cancer.

Methods

In the cross-sectional study direct bioimpedance measures (resistance, reactance, and phase angle) determined by bioelectrical impedance analysis (BIA) were performed on 31 patients with head and neck cancer and 31 healthy volunteers matched by age and sex as a control group.

Results

Phase angle at 50 kHz was found to be significantly lower (p = .000006) in patients with head and neck cancer than in the control group (4.69° ± 0.71 vs 5.59° ± 0.70, respectively). Resistance was significantly (p = .0002) greater in patients with head and neck cancer than in the control group (596.24 ± 96.31 ohm vs 513.73 ± 65.79 ohm, respectively).

Conclusion

Presurgical patients diagnosed with head and neck cancer have altered tissue electrical properties. Further observations would be valuable to calculate survival, validate the prognostic significance of phase angle, and monitor nutritional and therapeutic interventions in this patient population. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

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Volume35, Issue8

August 2013

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Altered tissue electrical properties in squamous cell carcinoma in head and neck tumors: Preliminary observations^†

Abstract

Background

Methods

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Conclusion

REFERENCES

Citing Literature

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Altered tissue electrical properties in squamous cell carcinoma in head and neck tumors: Preliminary observations†

Abstract

Background

Methods

Results

Conclusion

REFERENCES

Citing Literature

References

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Altered tissue electrical properties in squamous cell carcinoma in head and neck tumors: Preliminary observations^†