Visible Light-Induced C-5 Selective C—H Radical Borylation of Imidazo[1,2-a]pyridines with NHC-Boranes
Huitao Zheng
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorHao Lu
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorChaobo Su
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorRunlong Yang
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorLimin Zhao
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorCorresponding Author
Xiang Liu
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
E-mail: [email protected], [email protected]Search for more papers by this authorCorresponding Author
Hua Cao
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
E-mail: [email protected], [email protected]Search for more papers by this authorHuitao Zheng
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorHao Lu
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorChaobo Su
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorRunlong Yang
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorLimin Zhao
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
Search for more papers by this authorCorresponding Author
Xiang Liu
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
E-mail: [email protected], [email protected]Search for more papers by this authorCorresponding Author
Hua Cao
School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center, Guangdong Pharmaceutical University, Zhongshan, Guangdong, 528458 China
E-mail: [email protected], [email protected]Search for more papers by this authorComprehensive Summary
A visible-light-induced C-5 selective C—H borylation of imidazo[1,2-a]pyridines with NHC-BH3 via Minisci-type radical borylation reaction has been developed for the first time. The present sustainable protocol provides a new family of regioselectively C5-borylated imidazopyridines that would otherwise be difficult to prepare. It is a supplement to site-selective borylation of azines (nitrogen-containing aromatic heterocycles) and the assembly of sp2 carbon-boron bond.
Supporting Information
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Appendix S1: Supporting Information |
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