Volume 39, Issue 7 pp. 1849-1854
Concise Report

Ni2P Nanosheets: A High Catalytic Activity Platform for Electrochemical Detection of Acetaminophen

Ming Wei

Ming Wei

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

Kangda College of Nanjing Medical University, Lianyungang, Jiangsu, 222000 China

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Wenbo Lu

Corresponding Author

Wenbo Lu

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

E-mail: [email protected]; [email protected]Search for more papers by this author
Guoqin Liu

Guoqin Liu

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

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Yimin Jiang

Yimin Jiang

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

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Xuebo Liu

Xuebo Liu

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

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Liwei Bai

Liwei Bai

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

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Xiaowei Cao

Xiaowei Cao

Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, 225001 China

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Jianfeng Jia

Jianfeng Jia

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

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Haishun Wu

Corresponding Author

Haishun Wu

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University, Linfen, Shanxi, 041004 China

E-mail: [email protected]; [email protected]Search for more papers by this author
First published: 13 March 2021
Citations: 13

Main observation and conclusion

Accurate determination of acetaminophen concentration is essential for studying the metabolic status of acetaminophen in clinical practice. In this study, nickel phosphide was used for electrochemical detection of acetaminophen for the first time. An electrochemical acetaminophen sensor based on Ni2P nanosheets was successfully constructed and the sensor showed many convincing properties: (a) a good linear range (0.5 μmol/L—4.5 mmol/L); (b) a moderate sensitivity (131.1 μA·mmol–1·L·cm–2); (c) a low detection limit (0.107 μmol/L). In addition, the sensor also showed excellent selectivity, robust stability and reliable repeatability. Further experiments demonstrate that the prepared sensor can be used for quantitative detection of acetaminophen in commercial medical drugs.image

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