J&K Critical Review
N-Heterocyclic Carbene Organocatalysis: Activation Modes and Typical Reactive Intermediates
Xingkuan Chen,
Hongling Wang,
Zhichao Jin,
Yonggui Robin Chi,
Xingkuan Chen
Department of Chemistry, Jinan University, Guangzhou, Guangdong, 510632 China
ǂX.C.and H.W. contributed equally to this work.
Search for more papers by this authorHongling Wang
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
ǂX.C.and H.W. contributed equally to this work.
Search for more papers by this authorZhichao Jin
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
Search for more papers by this authorCorresponding Author
Yonggui Robin Chi
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore, 637371 Singapore
E-mail: [email protected]Search for more papers by this authorXingkuan Chen,
Hongling Wang,
Zhichao Jin,
Yonggui Robin Chi,
Xingkuan Chen
Department of Chemistry, Jinan University, Guangzhou, Guangdong, 510632 China
ǂX.C.and H.W. contributed equally to this work.
Search for more papers by this authorHongling Wang
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
ǂX.C.and H.W. contributed equally to this work.
Search for more papers by this authorZhichao Jin
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
Search for more papers by this authorCorresponding Author
Yonggui Robin Chi
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang, Guizhou, 550025 China
Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore, 637371 Singapore
E-mail: [email protected]Search for more papers by this authorAbstract
N-Heterocyclic carbene (NHC) organocatalysis has been developed as an important approach in modern organic synthesis. Versatile activation modes within NHC organocatalysis have been established with countless transformations being realized in both efficient and selective fashion. We would like to provide an overview on the key progresses achieved within this field in the past two decades. Since numerous excellent reviews have been documented within this area, we will mainly focus on the scientific development of this research field based on the basic reaction modes and typical reaction intermediates. 
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