Coronary Artery Disease
Why does FFR-guided PCI improve clinical outcomes? The missing link of post-PCI ischemia reduction
Key Points
- This study demonstrates that FFR-guided PCI reduces noninvasively assessed ischemia more effectively than angiography-guided PCI.
- Improved ischemia resolution was associated with improved clinical outcomes.
- Superior ischemia resolution is likely the dominant mechanism of improved outcomes with FFR in clinical outcome trials, as opposed to avoidance of inappropriate stenting and its associated adverse events.
CONFLICT OF INTEREST
Dr. Kern is a consultant and speaker for Abbott/St. Jude, Philips/Volcano, Acist Medical Inc., Opsens Inc., and Heartflow Inc.
Dr. Seto is a speaker for Acist Medical, Boston Scientific, Philips/Volcano.
