Water-soluble aldehyde-bearing polymers of 2-deoxy-2-methacrylamido-D-glucose for bone tissue engineering
Victor A. Korzhikov
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorSolvig Diederichs
Institute of Technical Chemistry, University of Hannover, Hannover, Germany
Search for more papers by this authorOlga V. Nazarova
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorEvgenia G. Vlakh
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorCornelia Kasper
Institute of Technical Chemistry, University of Hannover, Hannover, Germany
Search for more papers by this authorEvgeny F. Panarin
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorCorresponding Author
Tatiana B. Tennikova
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia===Search for more papers by this authorVictor A. Korzhikov
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorSolvig Diederichs
Institute of Technical Chemistry, University of Hannover, Hannover, Germany
Search for more papers by this authorOlga V. Nazarova
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorEvgenia G. Vlakh
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorCornelia Kasper
Institute of Technical Chemistry, University of Hannover, Hannover, Germany
Search for more papers by this authorEvgeny F. Panarin
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Search for more papers by this authorCorresponding Author
Tatiana B. Tennikova
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia
Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia===Search for more papers by this authorAbstract
In this study the methods of synthesis of hydrophilic aldehyde-bearing polymers and copolymers based on 2-deoxy-2-methacrylamido-D-glucose have been developed. Polymers with controllable aldehyde group content were synthesized via free-radical polymerization and subsequent polymeranalogous modification. The water-soluble polymers obtained were investigated in view of their capacity to be adsorbed on two commercial mineral supports used in bone tissue engineering. Besides, cytotoxicity of synthesized polymers was tested. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
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