Linear-Dendritic Alternating Copolymers
Haotian Sun
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorFarihah M. Haque
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorYi Zhang
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorAlex Commisso
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorMohamed Alaa Mohamed
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Department of Chemistry, Mansoura University, Mansoura, 35516 Egypt
Search for more papers by this authorProf. Marina Tsianou
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorProf. Honggang Cui
Department of Chemical & Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, 21218 USA
Search for more papers by this authorProf. Scott M. Grayson
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorCorresponding Author
Prof. Chong Cheng
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorHaotian Sun
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorFarihah M. Haque
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorYi Zhang
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorAlex Commisso
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorMohamed Alaa Mohamed
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Department of Chemistry, Mansoura University, Mansoura, 35516 Egypt
Search for more papers by this authorProf. Marina Tsianou
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorProf. Honggang Cui
Department of Chemical & Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, 21218 USA
Search for more papers by this authorProf. Scott M. Grayson
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorCorresponding Author
Prof. Chong Cheng
Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260 USA
Search for more papers by this authorGraphical Abstract
Spaced-out dendrons: Step-growth “click” polymerization using well-defined linear polymeric and dendritic reactants has led to linear-dendritic copolymers in which the linear segments serve as uniform spacers between the dendrons. With alternating hydrophilic linear blocks and hydrophobic dendrons, the copolymers can spontaneously self-assemble into a unique type of microphase-segregated nanorod in water.
Abstract
Herein, the design, synthesis, and characterization of an unprecedented copolymer consisting of alternating linear and dendritic segments is described. First, a 4th-generation Hawker-type dendron with two azide groups was synthesized, followed by a step-growth azide-alkyne “click” reaction between the 4th-generation diazido dendron and poly(ethylene glycol) diacetylene to create the target polymers. Unequal reactivity of the functional groups was observed in the step-growth polymerization. The resulting copolymers, with alternating hydrophilic linear and hydrophobic dendritic segments, can spontaneously associate into a unique type of microphase-segregated nanorods in water.
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