Decarboxylative Alkyl–Alkyl Cross-Coupling Reactions
Graphical Abstract
Alkyl with alkyl: A significant development in alkyl–alkyl cross-coupling reactions, namely the nickel-catalyzed decarboxylative Negishi coupling of N-hydroxyphthalimide esters, was recently reported by Baran and co-workers. This method enables the synthesis of various highly functionalized compounds, including natural product derivatives.