Malaria has long been a devastating and life-threatening global epidemic disease in human history. Artemisinin, the active substance against malaria, was first isolated and tested in the 1970s in China. The important role played by traditional Chinese medicine in the discovery of artemisinin is described by Y. Tu in her Nobel Lecture.

References

1Hippocrates, 400 B.C., On Airs, Waters, and Places, transl. F. Adams, Sydenham Society, London, 1849, pp. 179–222.
Google Scholar
2Inner Casnon of Yellow Emperor, Section 35, Chapter on Malaria.
Google Scholar
3“Bad air, amulets and mosquitoes: 2000 years of changing perspectives on malaria”: E. Hempelmann, K. Krafts, Malar. J. 2013, 12, 232.
10.1186/1475-2875-12-232
PubMed Web of Science® Google Scholar
(http://www.malariajournal.com/content/12/1/232).
Google Scholar
4Alphonse Laveran, Nobel Lecture: Protozoa as Causes of Diseases. December 11, 1907. http://www.nobelprize.org/nobel_prizes/medicine/laureates/1907/laveran-lecture.html.
Google Scholar
5R. Ross, Nobel Lecture, Researches on Malaria. December, 12, 1902. http://www.nobelprize.org/nobel_prizes/medicine/laureates/1902/ross-lecture.html.
Google Scholar
6“Plasmodium malariae: Parasite and Disease”: W. E. Collins, G. M. Jeffery, Clin. Microbiol. Rev. 2007, 4, 579–592.
10.1128/CMR.00027-07
Web of Science® Google Scholar
7National Institutes of Health National Institute of Allergy and Infectious Diseases (NIAID) Science Education, Understanding Malaria, Fighting an Ancient Scourge.
Google Scholar
8Centers for Disease Control and Prevention, Choosing a Drug to Prevent Malaria (http://www.cdc.gov/malaria/travelers/drugs.html).
Google Scholar
9WHO, Guidelines for the treatment of malaria, 3rd edition, April 2015.
Google Scholar
10WHO Global Plan for Artemisinin Resistance Containment (GPARC).
Google Scholar
11WHO emergency response to artemisinin resistance in the Greater Mekong Subregion.
Google Scholar
12Sheng Nong's Herbal Classic, Vol. 3.
Google Scholar
13Tu Youyou et al., Artemisia and Artemisinin Drugs, Chemical Industry Press, Beijing, 2009, p. 9.
Google Scholar
14“History of U.S. Military Contributions to the Study of Malaria”: COL C. F. Ockenhouse, Mil. Med. 2005, 170, 4–12.
Web of Science® Google Scholar
15Q. Wei-Chang, L. De-Pei, Chinese Famous Scientist of the 20th Century Academic Overview, Volume Medicine, Pharmacy, Science Press, Beijing, 2014, p. 333.
Google Scholar
16The National Leading Group Office for Malaria Control, Summary of National Malaria Control Research Meeting, 1st June 1971.
Google Scholar
17Tu Youyou et al., Artemisia and Artemisinin Drugs, Chemical Industry Press, Beijing, 2009, p. 40.
Google Scholar
18The National Leading Group Office for Malaria Control, Communication on Malaria Control Research, 5th November 1972.
Google Scholar
19Tu Youyou et al., Artemisia and Artemisinin Drugs, Chemical Industry Press, Beijing, 2009, pp. 45–56.
Google Scholar
20“Research Group for Artemisinin. A New Sesquiterpene Lactone-Artemisinin”: , Chin. Sci. Bull. 1977, 3, 142.
Google Scholar
21C. A. 1977, 87, 98788g.
Google Scholar
22Ge Hong, A Handbook of Prescriptions for Emergencies, Vol 3, Recipe No. 16 for Treating Cold and Fevers of Malaria, East Jin Dynasty, 300–400 A.D..
Google Scholar
23Tu Youyou et al., Artemisia and Artemisinin Drugs, Chemical Industry Press, Beijing, 2009, pp. 13–26.
Google Scholar
24WHO World Malaria Report 2014.
Google Scholar
25“Spread of Artemisinin Resistance in Plasmodium falciparum Malaria”: E. A. Ashley et al., N. Engl. J. Med. 2014, 371, 411–423.
10.1056/NEJMoa1314981
CAS PubMed Web of Science® Google Scholar

Citing Literature

Volume55, Issue35

August 22, 2016

Pages 10210-10226

This article also appears in:

Nobel Lectures

Artemisinin—A Gift from Traditional Chinese Medicine to the World (Nobel Lecture)^†

Graphical Abstract

References

Citing Literature

References

Information

About Wiley Online Library

Help & Support

Opportunities

Connect with Wiley

Artemisinin—A Gift from Traditional Chinese Medicine to the World (Nobel Lecture)†

Graphical Abstract

References

Citing Literature

References

Related

Information

Artemisinin—A Gift from Traditional Chinese Medicine to the World (Nobel Lecture)^†