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pH-Responsive Micro- and Nanocarrier Systems^†

M. Sc. Sabrina Nowag

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de

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Prof. Dr. Rainer Haag,

Corresponding Author

Prof. Dr. Rainer Haag

[email protected]

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de Search for more papers by this author

M. Sc. Sabrina Nowag,

M. Sc. Sabrina Nowag

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de

Search for more papers by this author

Prof. Dr. Rainer Haag,

Corresponding Author

Prof. Dr. Rainer Haag

[email protected]

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195 Berlin (Germany) http://www.polytree.de Search for more papers by this author

First published: 04 December 2013

https://doi.org/10.1002/anie.201308619

Citations: 86

^†

We thank the SFB 1112 of the German Research Foundation and the Helmholtz Virtual Institute for funding.

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Release on demand: The pH gradients between extra- and intracellular regions can be utilized for the controlled release of drugs and biological cargos from delivery systems. Biocompatible carrier systems with pH-cleavable units must fulfill many other criteria as well, for example, a long blood circulation time. This can be achieved by tailored micro- and nanocarriers based on macromolecular architectures or stable self-assembled systems.

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Volume53, Issue1

January 3, 2014

Pages 49-51

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pH-Responsive Micro- and Nanocarrier Systems^†