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Enantioselective Hydrogenation of Isoquinolines†
†
This work was supported by the DFG (Leibniz award) and the Alexander von Humboldt Foundation (D.Z.).
Graphical Abstract
N-H2eterocycles: Significant advances have been made in the development of the enantioselective partial or full hydrogenation of substituted isoquinolines and isoquinolinium and pyridinium salts. The products are valuable chiral 1,2,3,4-tetrahydroisoquinolines and piperidines (see scheme).
