Highly Regioselective Migration of the Sulfonyl Group: Easy Access to Functionalized Pyrroles†
Xiaoyi Xin
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorDr. Dongping Wang
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorDr. Xincheng Li
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorCorresponding Author
Prof. Dr. Boshun Wan
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)Search for more papers by this authorXiaoyi Xin
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorDr. Dongping Wang
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorDr. Xincheng Li
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Search for more papers by this authorCorresponding Author
Prof. Dr. Boshun Wan
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023 (China)Search for more papers by this authorWe are grateful to the National Natural Science Foundation of China (21172218) and the National Basic Research Program of China (2010CB833300) for financial support.
Graphical Abstract
Good migrations: The highly regioselective migration of a sulfonyl group for the synthesis of functionalized pyrroles is reported (see scheme; DMF=N,N-dimethylformamide). The migration of the sulfonyl group to different positions can be controlled with high selectivity, thus allowing the formation of both α- and β-(arylsulfonyl)methyl pyrroles with high yields.
Supporting Information
Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors.
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