Crystal Structure of a Molecular Assembly Line†
This research was supported by the Bundesministerium für Bildung und Forschung and the Deutsche Forschungsgemeinschaft.
Graphical Abstract
Domain event: Non-ribosomal peptide synthetases (NRPSs) are gigantic molecular machines which assemble natural products of high structural complexity in bacteria and fungi. A team of researchers has recently solved the first crystal structure of an entire module of domains from an NRPS system, a breakthrough achievement for the field.