Gold-Catalyzed Benzylic CH Activation at Room Temperature†
A. Stephen K. Hashmi Prof. Dr.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorSascha Schäfer Dipl.-Chem.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorMichael Wölfle Dipl.-Chem.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorCesar Diez Gil
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorPeter Fischer Dr.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorAntonio Laguna Prof. Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorM. Carmen Blanco Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorM. Concepción Gimeno Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorA. Stephen K. Hashmi Prof. Dr.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorSascha Schäfer Dipl.-Chem.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorMichael Wölfle Dipl.-Chem.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorCesar Diez Gil
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorPeter Fischer Dr.
Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany, Fax: (+49) 711-685-64321 http://www.hashmi.de
Search for more papers by this authorAntonio Laguna Prof. Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorM. Carmen Blanco Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorM. Concepción Gimeno Dr.
Departamento de Química Inorgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza-CSIC, 50009 Zaragoza, Spain, Fax: (+34) 976-761185
Search for more papers by this authorThis work was supported by the Fonds der Chemischen Industrie and by the European Union (AURICAT EU-RTN, HPRN-CT-2002-00174). C. Diez Gil is grateful for support by the Socrates/Erasmus Program of the EU.
Graphical Abstract
A tale of the unexpected: Coordinating and potentially chelating groups allow gold-catalyzed benzylic CH activation at room temperature. Substrates with additional nucleophilic substituents undergo unexpected dimerizations, in which eight new bonds are formed (see scheme).
Supporting Information
Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z701521_s.pdf or from the author.
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