Volume 46, Issue 12 pp. 2028-2030
Communication

In Vitro and Intracellular Production of Peptide-Encapsulated Fluorescent Silver Nanoclusters

Junhua Yu Dr.

Junhua Yu Dr.

School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452

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Sandeep A. Patel

Sandeep A. Patel

School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452

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Robert M. Dickson Prof.

Robert M. Dickson Prof.

School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452

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First published: 02 March 2007
Citations: 296

The authors gratefully acknowledge financial support from NSF BES-0323453, Invitrogen Corp., NIH R01M68732, and NIH P20072021, and thank Prof. D. F. Doyle for use of his cell-culture facility, and Prof. Y.-L. Tzeng for the gift of the peptides.

Graphical Abstract

Every nucleolus has a silver lining: Formation of silver nanoclusters by fluorescence photoactivation was used for the staining of cells at low silver nitrate concentrations and ambient temperature. The picture shows picosecond lifetime images of peptide-encapsulated silver nanoclusters within NIH 3T3 cells.

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