Bacterial colonization differences between central compartment atopic disease and eosinophilic chronic rhinosinusitis
Corresponding Author
Darren Rom MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Correspondence
Darren Rom, MD, 67 Burton Street Darlinghurst, NSW 2010, Australia.
Email: [email protected]
Search for more papers by this authorAndrea Sit MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
St Vincent's Clinical School, University of New South Wales, Sydney, Australia
Search for more papers by this authorRaquel Alvarado PhD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Search for more papers by this authorPeter Earls MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Department of Anatomical Pathology, St Vincent's Hospital, Sydney, Australia
Search for more papers by this authorJanet Rimmer MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Woolcock Institute, University of Sydney, Sydney, Australia
Faculty of Medicine, Notre Dame University, Sydney, Australia
Search for more papers by this authorRaewyn Campbell MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Royal Prince Alfred Hospital, Sydney, Australia
Search for more papers by this authorLarry Kalish MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Concord General Hospital, University of Sydney, Sydney, Australia
Search for more papers by this authorRaymond Sacks MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Concord General Hospital, University of Sydney, Sydney, Australia
Faculty of Medicine, University of Sydney, Sydney, Australia
Search for more papers by this authorRichard J. Harvey MD,PhD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Department of Anatomical Pathology, St Vincent's Hospital, Sydney, Australia
Search for more papers by this authorCorresponding Author
Darren Rom MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Correspondence
Darren Rom, MD, 67 Burton Street Darlinghurst, NSW 2010, Australia.
Email: [email protected]
Search for more papers by this authorAndrea Sit MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
St Vincent's Clinical School, University of New South Wales, Sydney, Australia
Search for more papers by this authorRaquel Alvarado PhD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Search for more papers by this authorPeter Earls MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Department of Anatomical Pathology, St Vincent's Hospital, Sydney, Australia
Search for more papers by this authorJanet Rimmer MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Woolcock Institute, University of Sydney, Sydney, Australia
Faculty of Medicine, Notre Dame University, Sydney, Australia
Search for more papers by this authorRaewyn Campbell MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Royal Prince Alfred Hospital, Sydney, Australia
Search for more papers by this authorLarry Kalish MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, University of Sydney, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Concord General Hospital, University of Sydney, Sydney, Australia
Search for more papers by this authorRaymond Sacks MD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia
Department of Otolaryngology, Head and Neck Surgery, Concord General Hospital, University of Sydney, Sydney, Australia
Faculty of Medicine, University of Sydney, Sydney, Australia
Search for more papers by this authorRichard J. Harvey MD,PhD
Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
Department of Anatomical Pathology, St Vincent's Hospital, Sydney, Australia
Search for more papers by this authorAbstract
Key Points
- Culturable bacterial colonization is similar between type 2 CRS phenotypes
- Staphylococcus aureus coinfection is similar between eosinophilic CRS and CCAD
- Patients with CCAD were younger, consistent with current knowledge of the disease
CONFLICT OF INTEREST STATEMENT
Richard J Harvey is consultant/advisory board with Medtronic, Novartis, GSK and Meda pharmaceuticals. Research grant funding received from GlaxoSmithKline. He has been on the speakers’ bureau for GlaxoSmithKline, AstraZeneca, Meda Pharmaceuticals, and Seqirus. All other authors have no financial disclosures or conflicts of interest.
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