Emerging 3D Printing Technologies to Develop Novel Pharmaceutical Formulations
Christos I. Gioumouxouzis1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
These authors equally contributed.Search for more papers by this authorGeorgios K. Eleftheriadis1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
Search for more papers by this authorDimitrios G. Fatouros1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
Search for more papers by this authorChristos I. Gioumouxouzis1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
These authors equally contributed.Search for more papers by this authorGeorgios K. Eleftheriadis1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
Search for more papers by this authorDimitrios G. Fatouros1
Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece
Search for more papers by this authorMohammed Maniruzzaman
School of Life Sciences, University of Sussex, Brighton, UK, BN1 9QG
Search for more papers by this authorSummary
This chapter present a wide variety of attempts to create three-dimensional (3D) printed pharmaceutical formulations, categorized by the specific additive manufacturing technique utilized for each one, that is fused deposition modeling (FDM), stereolithography (SLA), pressure-assisted microsyringes (PAM), selective laser sintering (SLS), powder bed printing (PBP), and inkjet printing (IP). FDM 3D printing was also employed in the manufacture of functional medical devices to prevent biofilm formation. PAM is a 3D printing method that enables the layer-by-layer formation of 3D objects via extrusion of a viscous polymeric ink on a building platform. One of the major concerns regarding the use of SLA 3D printing for biomedical applications is the toxicity of the substances used to trigger photopolymerization. PBP 3D printing is a method of rapid prototyping by selectively dispensing liquid binders on powder materials. SLS 3D printing is a technique similar to PBP. 3D inkjet printing is an alternative drop-on-demand approach on fabricating 3D structures.
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