Chapter 7

Emerging 3D Printing Technologies to Develop Novel Pharmaceutical Formulations

Christos I. Gioumouxouzis1

Christos I. Gioumouxouzis1

Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece

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Georgios K. Eleftheriadis1

Georgios K. Eleftheriadis1

Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece

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Dimitrios G. Fatouros1

Dimitrios G. Fatouros1

Aristotle University of Thessaloniki, Department of Pharmacy, Division of Pharmaceutical Technology, 54124, Thessaloniki, Greece

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First published: 14 December 2018
Citations: 1

Summary

This chapter present a wide variety of attempts to create three-dimensional (3D) printed pharmaceutical formulations, categorized by the specific additive manufacturing technique utilized for each one, that is fused deposition modeling (FDM), stereolithography (SLA), pressure-assisted microsyringes (PAM), selective laser sintering (SLS), powder bed printing (PBP), and inkjet printing (IP). FDM 3D printing was also employed in the manufacture of functional medical devices to prevent biofilm formation. PAM is a 3D printing method that enables the layer-by-layer formation of 3D objects via extrusion of a viscous polymeric ink on a building platform. One of the major concerns regarding the use of SLA 3D printing for biomedical applications is the toxicity of the substances used to trigger photopolymerization. PBP 3D printing is a method of rapid prototyping by selectively dispensing liquid binders on powder materials. SLS 3D printing is a technique similar to PBP. 3D inkjet printing is an alternative drop-on-demand approach on fabricating 3D structures.

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