Chapter 25
Antimicrobial and Antibiofilm Molecules Produced by Marine Bacteria
Florie Desriac,
Sophie Rodrigues,
Ibtissem Doghri,
Sophie Sablé,
Isabelle Lanneluc,
Yannick Fleury,
Alexis Bazire,
Alain Dufour,
Florie Desriac
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Univ. Brest, EA 3884, LBCM, IUEM, 2 rue de l'Université, 29000 Quimper France
These authors contributed equally to this work.Search for more papers by this authorSophie Rodrigues
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
These authors contributed equally to this work.Search for more papers by this authorIbtissem Doghri
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorSophie Sablé
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorIsabelle Lanneluc
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorYannick Fleury
Univ. Brest, EA 3884, LBCM, IUEM, 2 rue de l'Université, 29000 Quimper France
Search for more papers by this authorAlexis Bazire
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Search for more papers by this authorAlain Dufour
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Search for more papers by this authorFlorie Desriac,
Sophie Rodrigues,
Ibtissem Doghri,
Sophie Sablé,
Isabelle Lanneluc,
Yannick Fleury,
Alexis Bazire,
Alain Dufour,
Florie Desriac
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Univ. Brest, EA 3884, LBCM, IUEM, 2 rue de l'Université, 29000 Quimper France
These authors contributed equally to this work.Search for more papers by this authorSophie Rodrigues
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
These authors contributed equally to this work.Search for more papers by this authorIbtissem Doghri
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorSophie Sablé
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorIsabelle Lanneluc
Univ. La Rochelle, LIENSs, UMR 7266 Université de La Rochelle-CNRS, Avenue Michel Crépeau, 17042 La Rochelle Cedex 01 France
Search for more papers by this authorYannick Fleury
Univ. Brest, EA 3884, LBCM, IUEM, 2 rue de l'Université, 29000 Quimper France
Search for more papers by this authorAlexis Bazire
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Search for more papers by this authorAlain Dufour
Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, rue de Saint Maudé, 56100 Lorient France
Search for more papers by this authorStéphane La Barre,
Stephen S. Bates,
Stéphane La Barre
Sorbonne Université CNRS, Integrative Biology of Marine Models (LBI2M), Station Biologique de Roscoff (SBR), Roscoff, 29680 France
Search for more papers by this authorStephen S. Bates
Fisheries and Oceans Canada, Gulf Fisheries Centre, 343 Université Avenue, Moncton, 5030 Canada
Search for more papers by this authorBook Author(s):Stéphane La Barre,
Stephen S. Bates,
Stéphane La Barre
Sorbonne Université CNRS, Integrative Biology of Marine Models (LBI2M), Station Biologique de Roscoff (SBR), Roscoff, 29680 France
Search for more papers by this authorStephen S. Bates
Fisheries and Oceans Canada, Gulf Fisheries Centre, 343 Université Avenue, Moncton, 5030 Canada
Search for more papers by this authorSummary
Marine environments, and especially marine bacteria, constitute a rich source of producers of novel bioactive natural products with biotechnological interests. Novel effective molecules against antibiotic-resistant bacteria and against bacterial biofilms are needed in a variety of fields. This chapter is therefore devoted to reviewing antimicrobial and antibiofilm compounds produced by marine bacteria. Several types of molecules are considered, more particularly the antimicrobial tropodithietic acid and the nucleoside antibiotic A201A, as well as the antibiofilm molecules of different natures. Finally, particular attention is paid to the antimicrobial enzymes AlpP and lysine-epsilon-oxidase (LodA). Complementary studies of these enzymes have led to basic discoveries on the biofilm lifestyle of the producer bacteria, in addition to opening up possible future applications in industry, aquaculture, and human health.
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