Chapter 10
Halogenation and Vanadium Haloperoxidases
Jean-Baptiste Fournier,
Catherine Leblanc,
Jean-Baptiste Fournier
Sorbonne Universitées, UPMC Univ Paris 06, UMR, 8227
Integrative Biology of Marine Models, Station Biologique de Roscoff, CS, 90074, F-29688 Roscoff cedex, France
Search for more papers by this authorCatherine Leblanc
Integrative Biology of Marine Models, Station Biologique de Roscoff, CS, 90074, F-29688 Roscoff cedex, France
Search for more papers by this authorJean-Baptiste Fournier,
Catherine Leblanc,
Jean-Baptiste Fournier
Sorbonne Universitées, UPMC Univ Paris 06, UMR, 8227
Integrative Biology of Marine Models, Station Biologique de Roscoff, CS, 90074, F-29688 Roscoff cedex, France
Search for more papers by this authorCatherine Leblanc
Integrative Biology of Marine Models, Station Biologique de Roscoff, CS, 90074, F-29688 Roscoff cedex, France
Search for more papers by this authorBook Editor(s):Stéphane La Barre,
Jean-Michel Kornprobst,
Stéphane La Barre
Sorbonne Universités, UPMC Univ Paris 06, UMR 8227, Integrative Biology of Marine Models, Station Biologique de Roscoff, CS 90074, F-29688 Roscoff cedex, France
CNRS, UMR 8227, Integrative Biology of Marine Models, Station Biologique de Roscoff, CS 90074, F-29688 Roscoff cedex, France
Search for more papers by this authorJean-Michel Kornprobst
Institut Mer et Littoral,Bâtiment Isomer, 2, rue de la Houssinière, 44322 Nantes, BP 92208,Cedex 3, France
Search for more papers by this authorSummary
In marine organisms, vanadium haloperoxidases (VHPO) are involved in the production of halogenated metabolites, which feature a large panel of biological roles, such as signal molecules or antibiotics. VHPO-based halogenation processes are likely to play a role in the biogeochemical cycling of halogens because of the formation of volatile halocarbons, especially in marine coastal environments where large seaweed beds dominate. At the biochemical level, these enzymes present different specificities, and are classified according to the most electronegative halide that they can oxidize. In this chapter, a review is provided of all data obtained from biochemical, molecular characterization and structural studies on these haloperoxidases, since their discovery in a marine brown alga 30 years ago.
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