Transcatheter Interventions for Aortic Valve Insufficiency in Patients with Left Ventricular Assist Devices
Gabriel A. Hernandez
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorJoAnn Lindenfeld
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorSandip Zalawadiya
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorGabriel A. Hernandez
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorJoAnn Lindenfeld
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorSandip Zalawadiya
Cardiovascular Division, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA
Search for more papers by this authorEduardo J. de Marchena
International Medicine Institue, Miami, FL, United States
Search for more papers by this authorSummary
Aortic insufficiency (AI) is a common adverse event associated with continuous-flow left ventricular assist device (LVAD) support and can lead to serious outcomes, including mortality. Continuous ventricular unloading and prolonged asymmetric aortic valve (AV) closure result in leaflet fusion and myxoid degeneration, which may lead to pan-cyclic AI. Transcatheter aortic valve replacement (TAVR) has emerged as an off-label tool to overcome this maladaptive effect.
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