Chapter 20
Acute Relapsing Pancreatitis
What can be Done to Prevent Relapses?
Jorge D. Machicado,
Dhiraj Yadav,
Jorge D. Machicado
Division of Gastroenterology and Hepatology, Mayo Clinic Health System, Eau Claire, WI, USA
Search for more papers by this authorDhiraj Yadav
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Search for more papers by this authorJorge D. Machicado,
Dhiraj Yadav,
Jorge D. Machicado
Division of Gastroenterology and Hepatology, Mayo Clinic Health System, Eau Claire, WI, USA
Search for more papers by this authorDhiraj Yadav
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Search for more papers by this authorBook Editor(s):J. Enrique Domínguez-Muñoz MD, PhD,
J. Enrique Domínguez-Muñoz MD, PhD
Director
Department of Gastroenterology and Hepatology, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain
Search for more papers by this authorFirst published: 16 April 2021
Summary
Results of epidemiological and experimental studies suggest that acute pancreatitis (AP), recurrent acute pancreatitis (RAP), and chronic pancreatitis represent a disease continuum. In this chapter, the authors review the definition, epidemiology, etiological framework, and diagnostic work-up for RAP, risk stratification for disease progression, and approaches to prevent recurrences and progression. Risk factors associated with disease progression included etiology, ongoing alcohol and tobacco use, and number and severity of AP attacks. The basis for preventing recurrences and disease progression rests on an organized and rational diagnostic work-up. Targeted lifestyle, medical, endoscopic and surgical interventions can reduce the burden of RAP at different levels of prevention.
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